Replication data for PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus
This dataset includes the source data related to the submission of the article "PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus" to Nature Communications. It includes data about mRNA and protein regulation of PACAP-PAC1R system after a stress paradigm coupled with a...
| Autores: | , |
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| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:259560 |
| Acceso en línea: | https://ddd.uab.cat/record/259560 https://dx.doi.org/urn:doi:10.5565/ddd.uab.cat/259560 |
| Access Level: | acceso abierto |
| Palabra clave: | Fear Extinction PACAP |
| Sumario: | This dataset includes the source data related to the submission of the article "PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus" to Nature Communications. It includes data about mRNA and protein regulation of PACAP-PAC1R system after a stress paradigm coupled with a fear conditioning and fear extinction task. The effects of stress circuitry chemogenetic manipulation over PACAP-PAC1R regulation are also shown. Data from two cohorts of human participants are included, in the first cohort, the effects of the menstrual cycle over post-traumatic symptoms were investigated. In the second cohort, the effects of PACAP1R genotype in the SNP rs2267735 were investigated in a fear extinction task. |
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