Ulipristal acetate. A new emergency contraceptive: ethical aspects of its use

Current presentations ot the morning-after pill can be used effecti­vely for up to 72 hours after unprotected sexual intercourse. However, in some cases, the period can be shorter. For that rea­son, a pill, ulipristal acetate (Ellaone), which is licensed tor post­coital emergency contraception up to...

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Detalles Bibliográficos
Autor: Aznar Lucea, Justo
Tipo de recurso: artículo
Fecha de publicación:2010
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/1482
Acceso en línea:http://hdl.handle.net/20.500.12466/1482
Access Level:acceso abierto
Palabra clave:Contraceptives
Emergency contraception
Abortion
32 Ciencias Médicas
3104.11 Reproducción
71 Ética
Descripción
Sumario:Current presentations ot the morning-after pill can be used effecti­vely for up to 72 hours after unprotected sexual intercourse. However, in some cases, the period can be shorter. For that rea­son, a pill, ulipristal acetate (Ellaone), which is licensed tor post­coital emergency contraception up to 120 hours (5 days) following unprotected sexual intercourse or contraceptive failure, has now been marketed for the first time. An important aspect to be consider in the ethical assessment of any drug used in emergency contraception is its mechanism of action, as this assessment will be very different if the drug acts by inhibition or delaying the ovulation or by preventing the implanta­tion of the blastocyst in the maternal uterus, since in the lalter case would exert its action by terminating the life of an already li­ving embryo, Le. by an abortive mechanism. In relation to the Ellaone's mechanism of action, when the pill is taken five days before ovulation its action will be basically anti­conceptive, and the same if it is taken four days betorehand When it is taken three days before ovulation, it may be anticon­ceptive or by preventing implantation, but from then on, the me­chanism by which Ellaone may prevent unwanted pregnancies will be by an anti-implantation mechanism, in ott-Ier words, abortive. In summary, between 50% and 70% of the time, EI!aone will act by an abortive mechanism. It seems to us that this is the objective reality about the me­chanism of action of uliprital acetate (Ellaone), and therefore its anti-implantation effect will have to be taken into consideration when issuing an ethical judgement on its use.