Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA [Childhood and Environment Project]

Introduction: The INMA (INfancia y Medio Ambiente (Spanish for Environment and Childhood]) project is a cooperative research network. This project aims to study the effects of environment and diet on fetal and early childhood development. This article aims to present the air pollutant exposure proto...

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Detalles Bibliográficos
Autores: Esplugues, Ana, Fernandez-Patier, Rosalia, Aguilera, Inma, Inigueza, Carmen, Garcia Dos Santos, Saul, Aguirre Alfaro, Amelia, Lacasana, Marina, Estarlich, Marisa, Grimalt, Joan O., Fernandez, Marieta, Rebagliato, Marisa, Sala, Maria, Tardon, Adonina, Torrent, Maties, Dolores Martinez, Maria, Ribas-Fito, Nuria, Sunyer, Jordi, Ballester, Ferran
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p4088
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/4088
Access Level:acceso abierto
Palabra clave:air pollution
pregnancy
childhood
fetal development
cohort study
INMA
Descripción
Sumario:Introduction: The INMA (INfancia y Medio Ambiente (Spanish for Environment and Childhood]) project is a cooperative research network. This project aims to study the effects of environment and diet on fetal and early childhood development. This article aims to present the air pollutant exposure protocol during pregnancy and fetal and early childhood development of the INMA project. Methods: The information to assess air pollutant exposure during pregnancy is based on outdoor measurement of air pollutants (nitrogen dioxide [NO2], volatile organic compounds [VOC], ozone, particulate matter [PM10, PM2.5] and of their composition (polycyclic aromatic hydrocarbons]); measurement of indoor and personal exposure (VOC and NO2); urinary measurement of a biological marker of hydrocarbon exposure (1-hydroxypyrene); and data gathered by questionnaires and geographic information systems. These data allow individual air pollutant exposure indexes to be developed, which can then be used to analyze the possible effects of exposure on fetal development and child health. Conclusion: This protocol and the type of study allow an approximation to individual air pollutant exposure to be obtained. Finally, the large number of participants (N = 4,000), as well as their geographic and social diversity, increases the study's potential.

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