Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence

These data are associated with the population genomic analyses in Decroly et al. (2024).

Detalles Bibliográficos
Autores: Mackintosh, Alexander, Decroly, Thomas, Lohse, Konrad, Vila, Roger
Tipo de recurso: conjunto de datos
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/373347
Acceso en línea:http://hdl.handle.net/10261/373347
Access Level:acceso abierto
Palabra clave:Population genetics
Sex chromosomes
W chromosomes
Biological sciences
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spelling Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergenceMackintosh, AlexanderDecroly, ThomasLohse, KonradVila, RogerPopulation geneticsSex chromosomesW chromosomesBiological sciencesThese data are associated with the population genomic analyses in Decroly et al. (2024).Natural selection is less efficient in the absence of recombination. As a result, non-recombining sequences, such as sex chromosomes, tend to degenerate over time. Although the outcomes of recombination arrest are typically observed after many millions of generations, recent neo-sex chromosomes can give insight into the early stages of this process. Here we investigate the evolution of neo-sex chromosomes in the Spanish marbled white butterfly, Melanargia ines, where a Z-autosome fusion has turned the homologous autosome into a non-recombining neo-W chromosome. We show that these neo-sex chromosomes are likely limited to the Iberian population of M. ines, and that they arose around the time when this population split from North-African populations, around 1.5 million years ago. Recombination arrest of the neo-W chromosome has led to an excess of premature stop codons and frameshift mutations, and reduced gene expression compared to the neo-Z chromosome. Surprisingly, we identified two regions of 1 Mb at one end of the neo-W that are both less diverged from the neo-Z and less degraded than the rest of the chromosome, suggesting a history of rare but repeated genetic exchange between the two neo-sex chromosomes. These plateaus of neo-sex chromosome divergence suggest that neo-W degradation can be locally reversed by rare recombination between neo-W and neo-Z chromosomes.European Research Council, ModelGenomLand.Peer reviewedDryadEuropean Research CouncilVila, Roger [0000-0002-2447-4388]Mackintosh, Alexander [0009-0009-0238-8241]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242024info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1http://hdl.handle.net/10261/373347reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/EC/H2020/757648Decroly, Thomas; Vila, Roger; Lohse, Konrad; Mackintosh, Alexander. Rewinding the Ratchet: Rare Recombination Locally Rescues Neo-W Degeneration and Generates Plateaus of Sex-Chromosome Divergence. https://doi.org/10.1093/molbev/msae124 . http://hdl.handle.net/10261/373346Decroly, Thomas; Vila, Roger; Lohse, Konrad; Mackintosh, Alexander; 2024; Rewinding the ratchet: rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence [Preprint]; BioRxiv; https://doi.org/10.1101/2024.01.20.576444https://doi.org/10.5061/dryad.fj6q57435Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3733472026-05-22T06:33:51Z
dc.title.none.fl_str_mv Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
title Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
spellingShingle Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
Mackintosh, Alexander
Population genetics
Sex chromosomes
W chromosomes
Biological sciences
title_short Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
title_full Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
title_fullStr Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
title_full_unstemmed Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
title_sort Data from: Rewinding the ratchet: Rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence
dc.creator.none.fl_str_mv Mackintosh, Alexander
Decroly, Thomas
Lohse, Konrad
Vila, Roger
author Mackintosh, Alexander
author_facet Mackintosh, Alexander
Decroly, Thomas
Lohse, Konrad
Vila, Roger
author_role author
author2 Decroly, Thomas
Lohse, Konrad
Vila, Roger
author2_role author
author
author
dc.contributor.none.fl_str_mv European Research Council
Vila, Roger [0000-0002-2447-4388]
Mackintosh, Alexander [0009-0009-0238-8241]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Population genetics
Sex chromosomes
W chromosomes
Biological sciences
topic Population genetics
Sex chromosomes
W chromosomes
Biological sciences
description These data are associated with the population genomic analyses in Decroly et al. (2024).
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
format dataset
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/373347
url http://hdl.handle.net/10261/373347
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/EC/H2020/757648
Decroly, Thomas; Vila, Roger; Lohse, Konrad; Mackintosh, Alexander. Rewinding the Ratchet: Rare Recombination Locally Rescues Neo-W Degeneration and Generates Plateaus of Sex-Chromosome Divergence. https://doi.org/10.1093/molbev/msae124 . http://hdl.handle.net/10261/373346
Decroly, Thomas; Vila, Roger; Lohse, Konrad; Mackintosh, Alexander; 2024; Rewinding the ratchet: rare recombination locally rescues neo-W degeneration and generates plateaus of sex-chromosome divergence [Preprint]; BioRxiv; https://doi.org/10.1101/2024.01.20.576444
https://doi.org/10.5061/dryad.fj6q57435
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Dryad
publisher.none.fl_str_mv Dryad
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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