Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)

Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is don...

Descripción completa

Detalles Bibliográficos
Autores: Weitzer, Jakob, Castaño Vinyals, Gemma, Kogevinas, Manolis
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/48188
Acceso en línea:http://hdl.handle.net/10230/48188
http://dx.doi.org/10.1002/ijc.33310
Access Level:acceso abierto
Palabra clave:Breast
Cancer
Circadian disruption
Physical activity
Prostate
id ES_1a4e2d302a0ae20a0df55b00ac6732be
oai_identifier_str oai:recercat.cat:10230/48188
network_acronym_str ES
network_name_str España
repository_id_str
spelling Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)Weitzer, JakobCastaño Vinyals, GemmaKogevinas, ManolisBreastCancerCircadian disruptionPhysical activityProstateExperimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in-person interviews. Information on time-of-day of activity (assessed approximately 3 years after the assessment of lifetime physical activity and confounders) was available for 781 breast cancer cases, 865 population female controls, 504 prostate cases and 645 population male controls from 10 Spanish regions, 2008-2013. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for different activity timings compared to inactive subjects using unconditional logistic regression adjusting for confounders. Early morning (8-10 am) activity was associated with a protective effect compared to no physical activity for both breast (OR = 0.74, 95% CI = 0.48-1.15) and prostate cancer (OR = 0.73, 95% CI = 0.44-1.20); meta-OR for the two cancers combined 0.74 (95%CI = 0.53-1.02). There was no effect observed for breast or prostate cancer for late morning to afternoon activity while a protective effect was also observed for evening activity only for prostate cancer (OR = 0.75, 95% CI = 0.45-1.24). Protective effects of early morning activity were more pronounced for intermediate/evening chronotypes for both cancers. This is the first population-based investigation identifying a differential effect of timing of physical activity on cancer risk with more pronounced effects for morning hour activity. Our results, if confirmed, may improve current physical activity recommendations for cancer prevention.Wiley202120212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/48188http://dx.doi.org/10.1002/ijc.33310reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésCopyright © 2020 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of Union for International Cancer Control. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/481882026-05-29T05:05:01Z
dc.title.none.fl_str_mv Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
spellingShingle Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
Weitzer, Jakob
Breast
Cancer
Circadian disruption
Physical activity
Prostate
title_short Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_full Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_fullStr Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_full_unstemmed Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_sort Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
dc.creator.none.fl_str_mv Weitzer, Jakob
Castaño Vinyals, Gemma
Kogevinas, Manolis
author Weitzer, Jakob
author_facet Weitzer, Jakob
Castaño Vinyals, Gemma
Kogevinas, Manolis
author_role author
author2 Castaño Vinyals, Gemma
Kogevinas, Manolis
author2_role author
author
dc.subject.none.fl_str_mv Breast
Cancer
Circadian disruption
Physical activity
Prostate
topic Breast
Cancer
Circadian disruption
Physical activity
Prostate
description Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in-person interviews. Information on time-of-day of activity (assessed approximately 3 years after the assessment of lifetime physical activity and confounders) was available for 781 breast cancer cases, 865 population female controls, 504 prostate cases and 645 population male controls from 10 Spanish regions, 2008-2013. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for different activity timings compared to inactive subjects using unconditional logistic regression adjusting for confounders. Early morning (8-10 am) activity was associated with a protective effect compared to no physical activity for both breast (OR = 0.74, 95% CI = 0.48-1.15) and prostate cancer (OR = 0.73, 95% CI = 0.44-1.20); meta-OR for the two cancers combined 0.74 (95%CI = 0.53-1.02). There was no effect observed for breast or prostate cancer for late morning to afternoon activity while a protective effect was also observed for evening activity only for prostate cancer (OR = 0.75, 95% CI = 0.45-1.24). Protective effects of early morning activity were more pronounced for intermediate/evening chronotypes for both cancers. This is the first population-based investigation identifying a differential effect of timing of physical activity on cancer risk with more pronounced effects for morning hour activity. Our results, if confirmed, may improve current physical activity recommendations for cancer prevention.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/48188
http://dx.doi.org/10.1002/ijc.33310
url http://hdl.handle.net/10230/48188
http://dx.doi.org/10.1002/ijc.33310
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869404098304933888
score 15,811543

Similares en LA Referencia