Additive-Free Commercial Alumina Catalyzes the Halogen Exchange Reaction of Long Alkyl Halides in Batch and in Flow Processes
[EN] The synthesis of alkyl halides can be performed by simply halide exchange reactions between two different alkyl halides, catalyzed by aluminosilicates. Here, we show that commercially available alumina shows a superior catalytic activity for the halogen exchange reaction between long alkyl hali...
| Autores: | , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Universitat Politècnica de València (UPV) |
| Repositorio: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| Idioma: | inglés |
| OAI Identifier: | oai:riunet.upv.es:10251/209800 |
| Acesso em linha: | https://riunet.upv.es/handle/10251/209800 |
| Access Level: | acceso abierto |
| Palavra-chave: | Alumina Heterogeneous catalysis Inflow synthesis Halogen exchange reaction Alkyl halides |
| Resumo: | [EN] The synthesis of alkyl halides can be performed by simply halide exchange reactions between two different alkyl halides, catalyzed by aluminosilicates. Here, we show that commercially available alumina shows a superior catalytic activity for the halogen exchange reaction between long alkyl halides (more than 6 carbons), including fluorides, in either batch or flow modes. The catalytic activity of the solid alumina is modulated by alkaline countercations on the surface, and sodium-supported alumina shows the optimal performance for the iodo-bromo and iodo-fluoro exchange under inflow reaction conditions, after >24 h reaction time, without any external additive. |
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