Mechanics of Elastin-like Recombinamers hydrogels under mechanical wave pressure

The production of Elastin-like recombiners (ELR) has as objective the production of nano-structural devices that can be used for drug delivery and tissue engineering. The reason of why these materials are so desired are their good mechanical properties, biocompatibility, biodegradability and thermal...

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Detalles Bibliográficos
Autor: Riol Triviño, Alejandro
Tipo de recurso: tesis de maestría
Fecha de publicación:2020
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/43580
Acceso en línea:http://uvadoc.uva.es/handle/10324/43580
Access Level:acceso abierto
Palabra clave:Biomedicina
ELR
Propagación ondas mecánicas
Viscoelasticidad
Descripción
Sumario:The production of Elastin-like recombiners (ELR) has as objective the production of nano-structural devices that can be used for drug delivery and tissue engineering. The reason of why these materials are so desired are their good mechanical properties, biocompatibility, biodegradability and thermal sensitivity. The objective of this master thesis is to measure the propagation of mechanical waves inside an ELR hydrogel created in a 1:1 composition with two ELR biopolymers via click reaction. Using an oscilloscope, a wave generator and piezoelectrics we measured three Elastin- Like Recombinamers click gels at different PBS concentrations. The objective of the measurement is to understand the propagation of the mechanical waves in hydrogels depending on their composition and frequency of the mechanical waves. This is rather important because mechanical waves may influence the behaviour of a cell.