Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism

Atrial fibrillation; Mortality; Pulmonary embolism

Detalles Bibliográficos
Autores: Bikdeli, Behnood, Jiménez, David, del Toro, Jorge, Piazza, Gregory, Rivas, Agustina, Fernández-Reyes, José Luis, Suriñach Caralt, Jose Maria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Departament de Salut de la Generalitat de Catalunya (DS)
Repositorio:Scientia. Dipòsit d'Informació Digital del Departament de Salut
OAI Identifier:oai:scientiasalut.gencat.cat:11351/7460
Acceso en línea:https://hdl.handle.net/11351/7460
Access Level:acceso abierto
Palabra clave:Avaluació de resultats (Assistència sanitària)
Cor - Malalties - Diagnòstic
Embòlia pulmonar - Mortalitat
DISEASES::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Embolism::Pulmonary Embolism
Other subheadings::Other subheadings::Other subheadings::Other subheadings::/mortality
DISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation
Other subheadings::Other subheadings::/diagnosis
ENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::embolia y trombosis::embolia::embolia pulmonar
Otros calificadores::Otros calificadores::Otros calificadores::Otros calificadores::/mortalidad
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrial
Otros calificadores::Otros calificadores::/diagnóstico
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dc.title.none.fl_str_mv Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
title Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
spellingShingle Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
Bikdeli, Behnood
Avaluació de resultats (Assistència sanitària)
Cor - Malalties - Diagnòstic
Embòlia pulmonar - Mortalitat
DISEASES::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Embolism::Pulmonary Embolism
Other subheadings::Other subheadings::Other subheadings::Other subheadings::/mortality
DISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation
Other subheadings::Other subheadings::/diagnosis
ENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::embolia y trombosis::embolia::embolia pulmonar
Otros calificadores::Otros calificadores::Otros calificadores::Otros calificadores::/mortalidad
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrial
Otros calificadores::Otros calificadores::/diagnóstico
title_short Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
title_full Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
title_fullStr Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
title_full_unstemmed Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
title_sort Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
dc.creator.none.fl_str_mv Bikdeli, Behnood
Jiménez, David
del Toro, Jorge
Piazza, Gregory
Rivas, Agustina
Fernández-Reyes, José Luis
Suriñach Caralt, Jose Maria
author Bikdeli, Behnood
author_facet Bikdeli, Behnood
Jiménez, David
del Toro, Jorge
Piazza, Gregory
Rivas, Agustina
Fernández-Reyes, José Luis
Suriñach Caralt, Jose Maria
author_role author
author2 Jiménez, David
del Toro, Jorge
Piazza, Gregory
Rivas, Agustina
Fernández-Reyes, José Luis
Suriñach Caralt, Jose Maria
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Institut Català de la Salut
[Bikdeli B] Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. Yale/YNHH Center for Outcomes Research & Evaluation, New Haven, CT. Cardiovascular Research Foundation (CRF), New York, NY. [Jiménez D] Respiratory Department, Hospital Ramón y Cajal (IRYCIS), Madrid, Spain. Medicine Department, Universidad de Alcalá (IRYCIS), Madrid, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain. [Del Toro J] Department of Internal Medicine, Hospital General Universitario Gregorio Marañón, Madrid, Spain. [Piazza G] Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. [Rivas A] Department of Pneumonology, Hospital Universitario Araba, Álava, Spain. [Fernández-Reyes JL] Department of Internal Medicine, Complejo Hospitalario de Jaén, Jaén, Spain. [Suriñach JM] Servei de Medicina Interna, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Avaluació de resultats (Assistència sanitària)
Cor - Malalties - Diagnòstic
Embòlia pulmonar - Mortalitat
DISEASES::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Embolism::Pulmonary Embolism
Other subheadings::Other subheadings::Other subheadings::Other subheadings::/mortality
DISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation
Other subheadings::Other subheadings::/diagnosis
ENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::embolia y trombosis::embolia::embolia pulmonar
Otros calificadores::Otros calificadores::Otros calificadores::Otros calificadores::/mortalidad
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrial
Otros calificadores::Otros calificadores::/diagnóstico
topic Avaluació de resultats (Assistència sanitària)
Cor - Malalties - Diagnòstic
Embòlia pulmonar - Mortalitat
DISEASES::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Embolism::Pulmonary Embolism
Other subheadings::Other subheadings::Other subheadings::Other subheadings::/mortality
DISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation
Other subheadings::Other subheadings::/diagnosis
ENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::embolia y trombosis::embolia::embolia pulmonar
Otros calificadores::Otros calificadores::Otros calificadores::Otros calificadores::/mortalidad
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrial
Otros calificadores::Otros calificadores::/diagnóstico
description Atrial fibrillation; Mortality; Pulmonary embolism
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/7460
url https://hdl.handle.net/11351/7460
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Journal of the American Heart Association;10(17)
https://doi.org/10.1161/JAHA.121.021467
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv Scientia
reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname:Departament de Salut de la Generalitat de Catalunya (DS)
instname_str Departament de Salut de la Generalitat de Catalunya (DS)
reponame_str Scientia. Dipòsit d'Informació Digital del Departament de Salut
collection Scientia. Dipòsit d'Informació Digital del Departament de Salut
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869403966286069760
spelling Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary EmbolismBikdeli, BehnoodJiménez, Daviddel Toro, JorgePiazza, GregoryRivas, AgustinaFernández-Reyes, José LuisSuriñach Caralt, Jose MariaAvaluació de resultats (Assistència sanitària)Cor - Malalties - DiagnòsticEmbòlia pulmonar - MortalitatDISEASES::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Embolism::Pulmonary EmbolismOther subheadings::Other subheadings::Other subheadings::Other subheadings::/mortalityDISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial FibrillationOther subheadings::Other subheadings::/diagnosisENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::embolia y trombosis::embolia::embolia pulmonarOtros calificadores::Otros calificadores::Otros calificadores::Otros calificadores::/mortalidadENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrialOtros calificadores::Otros calificadores::/diagnósticoAtrial fibrillation; Mortality; Pulmonary embolismFibrilación auricular; Mortalidad; Embolia pulmonarFibril·lació auricular; Mortalitat; Embòlia pulmonarBackground Atrial fibrillation (AF) may exist before or occur early in the course of pulmonary embolism (PE). We determined the PE outcomes based on the presence and timing of AF. Methods and Results Using the data from a multicenter PE registry, we identified 3 groups: (1) those with preexisting AF, (2) patients with new AF within 2 days from acute PE (incident AF), and (3) patients without AF. We assessed the 90‐day and 1‐year risk of mortality and stroke in patients with AF, compared with those without AF (reference group). Among 16 497 patients with PE, 792 had preexisting AF. These patients had increased odds of 90‐day all‐cause (odds ratio [OR], 2.81; 95% CI, 2.33–3.38) and PE‐related mortality (OR, 2.38; 95% CI, 1.37–4.14) and increased 1‐year hazard for ischemic stroke (hazard ratio, 5.48; 95% CI, 3.10–9.69) compared with those without AF. After multivariable adjustment, preexisting AF was associated with significantly increased odds of all‐cause mortality (OR, 1.91; 95% CI, 1.57–2.32) but not PE‐related mortality (OR, 1.50; 95% CI, 0.85–2.66). Among 16 497 patients with PE, 445 developed new incident AF within 2 days of acute PE. Incident AF was associated with increased odds of 90‐day all‐cause (OR, 2.28; 95% CI, 1.75–2.97) and PE‐related (OR, 3.64; 95% CI, 2.01–6.59) mortality but not stroke. Findings were similar in multivariable analyses. Conclusions In patients with acute symptomatic PE, both preexisting AF and incident AF predict adverse clinical outcomes. The type of adverse outcomes may differ depending on the timing of AF onset.None.WileyInstitut Català de la Salut[Bikdeli B] Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. Yale/YNHH Center for Outcomes Research & Evaluation, New Haven, CT. Cardiovascular Research Foundation (CRF), New York, NY. [Jiménez D] Respiratory Department, Hospital Ramón y Cajal (IRYCIS), Madrid, Spain. Medicine Department, Universidad de Alcalá (IRYCIS), Madrid, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain. [Del Toro J] Department of Internal Medicine, Hospital General Universitario Gregorio Marañón, Madrid, Spain. [Piazza G] Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. [Rivas A] Department of Pneumonology, Hospital Universitario Araba, Álava, Spain. [Fernández-Reyes JL] Department of Internal Medicine, Complejo Hospitalario de Jaén, Jaén, Spain. [Suriñach JM] Servei de Medicina Interna, Vall d’Hebron Hospital Universitari, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202220222021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/7460Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésJournal of the American Heart Association;10(17)https://doi.org/10.1161/JAHA.121.021467Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/74602026-06-12T09:38:37Z
score 15,811543

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