Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts

This article belongs to the Special Issue "Recent Advances in Plant Phenolics".-- This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license.

Detalles Bibliográficos
Autores: Navarro-Hoyos, Mirtha, Sánchez-Patán, Fernando, Murillo Masis, Renato, Martín-Álvarez, Pedro J., Zamora Ramirez, William, Monagas Juan, María Josefina, Bartolomé, Begoña
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/128548
Acceso en línea:http://hdl.handle.net/10261/128548
Access Level:acceso abierto
Palabra clave:Uncaria tomentosa L.
Alkaloids
UPLC
TQ-ESI/MS
Flavonoids
13C NMR
Proanthocyanidins
Propelargonidins
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spelling Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extractsNavarro-Hoyos, MirthaSánchez-Patán, FernandoMurillo Masis, RenatoMartín-Álvarez, Pedro J.Zamora Ramirez, WilliamMonagas Juan, María JosefinaBartolomé, BegoñaUncaria tomentosa L.AlkaloidsUPLCTQ-ESI/MSFlavonoids13C NMRProanthocyanidinsPropelargonidinsThis article belongs to the Special Issue "Recent Advances in Plant Phenolics".-- This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license.The phenolic composition of extracts from Uncaria tomentosa L. from different regions of Costa Rica was studied using advanced analytical techniques such as UPLC/TQ-ESI-MS and 13C-NMR. Samples from leaves, stems, bark and wood (n = 22) were subjected to extraction to obtain phenolic and alkaloid extracts, separately. Comparatively, higher values of total phenolic content were observed for leaves, stems and bark (225–494 gallic acid equivalents/g) than for wood extracts (40–167 gallic acid equivalents/g). A total of 32 non-flavonoid and flavonoid compounds were identified in the phenolic extracts: hydroxybenzoic acids (benzoic, salicylic, 4-hydroxybenzoic, prochatechuic, gallic, syringic and vanillic acids), hydroxycinnamic acids (p-coumaric, caffeic, ferulic and isoferulic acids), flavan-3-ols monomers [(+)-catechin and (−)-epicatechin)], procyanidin dimers (B1, B2, B3, B4, B5, B7 and two other of unknown structure) and trimers (C1, T2 and one of unknown structure), flavalignans (four unknown structures pertaining to the cinchonain family) and propelargonidin dimers (four unknown structures, reported for the first time in U. tomentosa). Additionally, alkaloid extracts obtained from the plant residue after phenolic extraction exhibited a content of tetracyclic and pentacyclic alkaloids ranging between 95 and 275 mg/100 g of dry material for bark extracts, and between 30 and 704 mg/100 g for leaves extracts. In addition, a minor alkaloid was isolated and characterized, namely 18,19-dehydrocorynoxinoic acid. Our results confirmed the feasibility of U. tomentosa as a suitable raw material for obtaining phenolic- and alkaloid-rich extracts of potential interest.This project was partially funded by a grant from the Spanish International Development Cooperation Agency (AECID) (Refs. A/023397/09 and A/030037/10) and a joint grant from the Costa Rica-USA Foundation (CRUSA) and the Spanish Scientific Research Council (CSIC) (Ref. CR0024).We acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI).Peer reviewedMultidisciplinary Digital Publishing InstituteMinisterio de Asuntos Exteriores y Cooperación (España)Fundación CRUSAConsejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201620162015info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/128548reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.3390/molecules201219875Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1285482026-05-22T06:33:51Z
dc.title.none.fl_str_mv Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
title Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
spellingShingle Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
Navarro-Hoyos, Mirtha
Uncaria tomentosa L.
Alkaloids
UPLC
TQ-ESI/MS
Flavonoids
13C NMR
Proanthocyanidins
Propelargonidins
title_short Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
title_full Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
title_fullStr Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
title_full_unstemmed Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
title_sort Phenolic assesment of Uncaria tomentosa L. (cat’s claw): Leaves, stem, bark and wood extracts
dc.creator.none.fl_str_mv Navarro-Hoyos, Mirtha
Sánchez-Patán, Fernando
Murillo Masis, Renato
Martín-Álvarez, Pedro J.
Zamora Ramirez, William
Monagas Juan, María Josefina
Bartolomé, Begoña
author Navarro-Hoyos, Mirtha
author_facet Navarro-Hoyos, Mirtha
Sánchez-Patán, Fernando
Murillo Masis, Renato
Martín-Álvarez, Pedro J.
Zamora Ramirez, William
Monagas Juan, María Josefina
Bartolomé, Begoña
author_role author
author2 Sánchez-Patán, Fernando
Murillo Masis, Renato
Martín-Álvarez, Pedro J.
Zamora Ramirez, William
Monagas Juan, María Josefina
Bartolomé, Begoña
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Asuntos Exteriores y Cooperación (España)
Fundación CRUSA
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Uncaria tomentosa L.
Alkaloids
UPLC
TQ-ESI/MS
Flavonoids
13C NMR
Proanthocyanidins
Propelargonidins
topic Uncaria tomentosa L.
Alkaloids
UPLC
TQ-ESI/MS
Flavonoids
13C NMR
Proanthocyanidins
Propelargonidins
description This article belongs to the Special Issue "Recent Advances in Plant Phenolics".-- This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license.
publishDate 2015
dc.date.none.fl_str_mv 2015
2016
2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/128548
url http://hdl.handle.net/10261/128548
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.3390/molecules201219875
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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