The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function [Dataset]

Table S1. Differentially expressed genes in Vav2(Onc) and Vav2(–/–);Vav3(–/–) skin stem cells. Table S2A. Differentially expressed genes in WT TSCs vs SSCs. Table S3. Differentially expressed genes in Vav2(Onc) and WT tumor stem cells. FIGURE S1. Vav function regulates SSC numbers. FIGURE S2. The Va...

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Detalles Bibliográficos
Autores: Lorenzo-Martín, L. Francisco, Menacho-Márquez, Mauricio, Fernández-Parejo, Natalia, Rodríguez-Fdez, Sonia, Pascual, Gloria, Abad, Antonio, Crespo, Piero, Dosil, Mercedes, Benitah, Salvador A., Bustelo, Xosé R.
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/330911
Acceso en línea:http://hdl.handle.net/10261/330911
Access Level:acceso abierto
Descripción
Sumario:Table S1. Differentially expressed genes in Vav2(Onc) and Vav2(–/–);Vav3(–/–) skin stem cells. Table S2A. Differentially expressed genes in WT TSCs vs SSCs. Table S3. Differentially expressed genes in Vav2(Onc) and WT tumor stem cells. FIGURE S1. Vav function regulates SSC numbers. FIGURE S2. The Vav-dependent skin phenotype is mostly keratinocyte-autonomous. FIGURE S3. Vav proteins regulate transcriptional programs involved in stem cell homeostasis. FIGURE S4. Vav2Onc SSC transcriptome cross-comparison. FIGURE S5. Impact of Vav2Onc catalysis-dependent signaling in tumor stem cells.

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