Viroids: the minimal non-coding RNAs with autonomous replication

Viroids are small (246-401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate in the nucleus and chloroplast, respectively. Replication occurs by an RNA-based roll...

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Detalles Bibliográficos
Autores: Flores, Ricardo, Delgado, Sonia, Gas, María-Eugenia, Carbonell, Alberto, Molina, Diego, Gago, Selma, De la Peña, Marcos
Tipo de recurso: artículo
Fecha de publicación:2004
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/343161
Acceso en línea:http://hdl.handle.net/10261/343161
https://api.elsevier.com/content/abstract/scopus_id/2542457425
Access Level:acceso abierto
Palabra clave:Catalytic RNA | Hammerhead ribozyme | RNA silencing | Viroid
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spelling Viroids: the minimal non-coding RNAs with autonomous replicationFlores, RicardoDelgado, SoniaGas, María-EugeniaCarbonell, AlbertoMolina, DiegoGago, SelmaDe la Peña, MarcosCatalytic RNA | Hammerhead ribozyme | RNA silencing | ViroidViroids are small (246-401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate in the nucleus and chloroplast, respectively. Replication occurs by an RNA-based rolling-circle mechanism in three steps: (1). synthesis of longer-than-unit strands catalyzed by host DNA-dependent RNA polymerases forced to transcribe RNA templates, (2). processing to unit-length, which in family Avsunviroidae is mediated by hammerhead ribozymes, and (3). circularization either through an RNA ligase or autocatalytically. Disease induction might result from the accumulation of viroid-specific small interfering RNAs that, via RNA silencing, could interfere with normal developmental pathways.Peer reviewed#NODATA##NODATA##NODATA##NODATA##NODATA##NODATA##NODATA#Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242004info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/343161https://api.elsevier.com/content/abstract/scopus_id/2542457425reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésFEBS lettersSíinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3431612026-05-22T06:33:51Z
dc.title.none.fl_str_mv Viroids: the minimal non-coding RNAs with autonomous replication
title Viroids: the minimal non-coding RNAs with autonomous replication
spellingShingle Viroids: the minimal non-coding RNAs with autonomous replication
Flores, Ricardo
Catalytic RNA | Hammerhead ribozyme | RNA silencing | Viroid
title_short Viroids: the minimal non-coding RNAs with autonomous replication
title_full Viroids: the minimal non-coding RNAs with autonomous replication
title_fullStr Viroids: the minimal non-coding RNAs with autonomous replication
title_full_unstemmed Viroids: the minimal non-coding RNAs with autonomous replication
title_sort Viroids: the minimal non-coding RNAs with autonomous replication
dc.creator.none.fl_str_mv Flores, Ricardo
Delgado, Sonia
Gas, María-Eugenia
Carbonell, Alberto
Molina, Diego
Gago, Selma
De la Peña, Marcos
author Flores, Ricardo
author_facet Flores, Ricardo
Delgado, Sonia
Gas, María-Eugenia
Carbonell, Alberto
Molina, Diego
Gago, Selma
De la Peña, Marcos
author_role author
author2 Delgado, Sonia
Gas, María-Eugenia
Carbonell, Alberto
Molina, Diego
Gago, Selma
De la Peña, Marcos
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv #NODATA#
#NODATA#
#NODATA#
#NODATA#
#NODATA#
#NODATA#
#NODATA#
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Catalytic RNA | Hammerhead ribozyme | RNA silencing | Viroid
topic Catalytic RNA | Hammerhead ribozyme | RNA silencing | Viroid
description Viroids are small (246-401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate in the nucleus and chloroplast, respectively. Replication occurs by an RNA-based rolling-circle mechanism in three steps: (1). synthesis of longer-than-unit strands catalyzed by host DNA-dependent RNA polymerases forced to transcribe RNA templates, (2). processing to unit-length, which in family Avsunviroidae is mediated by hammerhead ribozymes, and (3). circularization either through an RNA ligase or autocatalytically. Disease induction might result from the accumulation of viroid-specific small interfering RNAs that, via RNA silencing, could interfere with normal developmental pathways.
publishDate 2004
dc.date.none.fl_str_mv 2004
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/343161
https://api.elsevier.com/content/abstract/scopus_id/2542457425
url http://hdl.handle.net/10261/343161
https://api.elsevier.com/content/abstract/scopus_id/2542457425
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv FEBS letters
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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