Advances in multimodal treatment for stage IIIA-N2 non-small cell lung cancer

Background and aim: In stage IIIA-N2 non-small cell lung cancer (NSCLC), the accuracy of combined positron-emission tomography/computed tomography imaging (PET-CT), together with mediastinal staging techniques, has led to a wide range of challenging clinical scenarios in terms of therapeutic managem...

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Detalles Bibliográficos
Autores: Montemuiño, Sara, Marcos Sánchez, Soraya, Calzas Rodríguez, Julia, Losada Vila, Beatriz, Llorente Herrero, Esther, Hisado Díaz, María Dolores, Busto González, Victoria Valeri, Taboada, Begoña, Vaquero Barrón, Blanca, Couñago Lorenzo, Felipe, Et al.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/11358
Acceso en línea:http://hdl.handle.net/11268/11358
Access Level:acceso abierto
Palabra clave:Neoplasias pulmonares
Terapia Combinada
Quimioterapia
Cáncer
Tratamiento médico
Descripción
Sumario:Background and aim: In stage IIIA-N2 non-small cell lung cancer (NSCLC), the accuracy of combined positron-emission tomography/computed tomography imaging (PET-CT), together with mediastinal staging techniques, has led to a wide range of challenging clinical scenarios in terms of therapeutic management. Concurrent chemoradiotherapy followed by consolidation immunotherapy remains the standard of care. In patients with potentially-resectable disease, surgery plays an important role in multimodal therapy. The introduction of targeted therapies and immune-checkpoint inhibitors have revolutionized multimodal treatment. In the present article, we review current treatment options and future trends in stage IIIA-N2 NSCLC. Relevance for patients: This article provides insight into the current status of multimodal treatment for NSCLC to support decision-making in routine clinical practice.