New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti- Mycobacterium tuberculosis agents.

Mycobacterium tuberculosis (M.Tb) is a bacillus capable of causing a chronic and fatal condition in humans known as tuberculosis (TB). It is estimated that there are 8 million new cases of TB per year and 3.1 million infected people die annually. Thirty-six new amide quinoxaline 1,4-di-N-oxide deriv...

Descripción completa

Detalles Bibliográficos
Autores: Monge, A. (Antonio)|||/items/804a350e-c7ff-4318-9742-cdc3432eb2a8, Aldana, I. (Ignacio)|||/items/2a317afc-d6ab-4970-8bac-41d9715f5618, Pérez-Silanes, S. (Silvia)|||/items/e5734c65-2dd8-4fdd-a74a-fc7526136c45, Torres, E. (Enrique)|||/items/63f6c247-849f-4192-9a16-b86398ba3fc5, Burguete, A. (Asunción)|||/items/841509d2-131f-45ab-97cb-0e072035c61e, Villar, R. (Raquel)|||/items/8b76d05b-786e-4baa-8e1f-5d29011d72fd, Solano, B. (Beatriz)|||/items/f8ed6dbf-02f6-4dec-8dcc-af6680ab51e5, Moreno-de-Viguri, E. (Elsa)|||/items/08473f69-a6ab-4896-8cf9-41e6daf12bfa, Ancizu, S. (Saioa)|||/items/b7ddb356-5d8e-4be4-a223-63fbcd1a34e7
Tipo de recurso: artículo
Fecha de publicación:2010
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/35790
Acceso en línea:https://hdl.handle.net/10171/35790
Access Level:acceso abierto
Palabra clave:Rifampin
Mycobacterium tuberculosis
Quinoxaline 1,4-di-N-oxide
Anti-tuberculosis agents
Descripción
Sumario:Mycobacterium tuberculosis (M.Tb) is a bacillus capable of causing a chronic and fatal condition in humans known as tuberculosis (TB). It is estimated that there are 8 million new cases of TB per year and 3.1 million infected people die annually. Thirty-six new amide quinoxaline 1,4-di-N-oxide derivatives have been synthesized and evaluated as potential anti-tubercular agents,obtaining biological values similar to the reference compound, Rifampin (RIF).

Similares en LA Referencia