Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection

The cortico-cortical evoked potentials (CCEP) are a relatively recent intraoperative monitoring tool that has shown high reliability in detecting the functional language area and its connections. In this work we describe a patient with a tumor located in the language area who underwent tumor resecti...

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Detalles Bibliográficos
Autores: Vega-Zelaya, Lorena, Navas, Marta, Pastor, Jesús, Martín Plasencia, Pilar
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/709853
Acceso en línea:http://hdl.handle.net/10486/709853
https://dx.doi.org/10.31487/j.SCR.2020.12.09
Access Level:acceso abierto
Palabra clave:anaesthetized surgery
awake surgery
cortical mapping
cortico-cortical evoked potentials
intraoperative neurophysiological
monitoring
Psicología
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spelling Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resectionVega-Zelaya, LorenaNavas, MartaPastor, JesúsMartín Plasencia, Pilaranaesthetized surgeryawake surgerycortical mappingcortico-cortical evoked potentialsintraoperative neurophysiologicalmonitoringPsicologíaThe cortico-cortical evoked potentials (CCEP) are a relatively recent intraoperative monitoring tool that has shown high reliability in detecting the functional language area and its connections. In this work we describe a patient with a tumor located in the language area who underwent tumor resection. A neurophysiological intraoperative mapping of the frontal and posterior language area with the anesthetized patient was carried out. Then the patient was awaked. To demonstrate the relationship between language function and CCEP, the Ojemann’s stimulation technique was used in the same electrodes were CCEPs were obtained. An alteration in the emission of language had been found on the electrodes where CCEP was obtained and in adjacent electrodes. During tumor resection we used a double check for language function: neurological evaluation and CCEPs. We obtained a biunivocal relationship between warning criteria in the CCEP and immediate language impairment on neurological examination. We always observed a significant decrease in the CCEP associated with language impairment. The CCEP are able to obtain information in real time with a good spatial resolution of the language function. Future studies should be carried out in order to analyse the robustness of this technique to perform it in anesthetized patientsThis work was financed by a grant from the Ministerio de Sanidad FIS PI17/02193 and was partially supported by FEDER (Fonds Europeen de Developpement Economique et Regional)Science RepositoryDepartamento de Psicología Biológica y de la SaludFacultad de Psicología20202020-12-10research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10486/709853https://dx.doi.org/10.31487/j.SCR.2020.12.09reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/7098532026-06-23T12:46:27Z
dc.title.none.fl_str_mv Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
title Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
spellingShingle Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
Vega-Zelaya, Lorena
anaesthetized surgery
awake surgery
cortical mapping
cortico-cortical evoked potentials
intraoperative neurophysiological
monitoring
Psicología
title_short Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
title_full Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
title_fullStr Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
title_full_unstemmed Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
title_sort Utility of intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection
dc.creator.none.fl_str_mv Vega-Zelaya, Lorena
Navas, Marta
Pastor, Jesús
Martín Plasencia, Pilar
author Vega-Zelaya, Lorena
author_facet Vega-Zelaya, Lorena
Navas, Marta
Pastor, Jesús
Martín Plasencia, Pilar
author_role author
author2 Navas, Marta
Pastor, Jesús
Martín Plasencia, Pilar
author2_role author
author
author
dc.contributor.none.fl_str_mv Departamento de Psicología Biológica y de la Salud
Facultad de Psicología
dc.subject.none.fl_str_mv anaesthetized surgery
awake surgery
cortical mapping
cortico-cortical evoked potentials
intraoperative neurophysiological
monitoring
Psicología
topic anaesthetized surgery
awake surgery
cortical mapping
cortico-cortical evoked potentials
intraoperative neurophysiological
monitoring
Psicología
description The cortico-cortical evoked potentials (CCEP) are a relatively recent intraoperative monitoring tool that has shown high reliability in detecting the functional language area and its connections. In this work we describe a patient with a tumor located in the language area who underwent tumor resection. A neurophysiological intraoperative mapping of the frontal and posterior language area with the anesthetized patient was carried out. Then the patient was awaked. To demonstrate the relationship between language function and CCEP, the Ojemann’s stimulation technique was used in the same electrodes were CCEPs were obtained. An alteration in the emission of language had been found on the electrodes where CCEP was obtained and in adjacent electrodes. During tumor resection we used a double check for language function: neurological evaluation and CCEPs. We obtained a biunivocal relationship between warning criteria in the CCEP and immediate language impairment on neurological examination. We always observed a significant decrease in the CCEP associated with language impairment. The CCEP are able to obtain information in real time with a good spatial resolution of the language function. Future studies should be carried out in order to analyse the robustness of this technique to perform it in anesthetized patients
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-12-10
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10486/709853
https://dx.doi.org/10.31487/j.SCR.2020.12.09
url http://hdl.handle.net/10486/709853
https://dx.doi.org/10.31487/j.SCR.2020.12.09
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Science Repository
publisher.none.fl_str_mv Science Repository
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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