Human Rotavirus G9 and G3 as Major Cause of Diarrhea in Hospitalized Children, Spain

In Spain, diarrhea remains a major cause of illness among infants and young children. To determine the prevalence of rotavirus genotypes and temporal and geographic differences in strain distribution, a structured surveillance study of hospitalized children <5 years of age with diarrhea was initi...

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Detalles Bibliográficos
Autores: Sanchez-Fauquier, Alicia, Montero, Vanessa, Moreno, Silvia, Sole, Monica, Colomina, Javier, Iturriza-Gomara, Miren, Revilla, Ana, Wilhelmi, Isabel, Gray, Jim, Gegavi/VIGESS-Net Group
Tipo de recurso: artículo
Fecha de publicación:2006
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/6994
Acceso en línea:http://hdl.handle.net/20.500.12105/6994
Access Level:acceso abierto
Palabra clave:Base Sequence
Child, Preschool
Diarrhea
Humans
Infant
Infant, Newborn
Prevalence
Reverse Transcriptase Polymerase Chain Reaction
Rotavirus
Spain
Descripción
Sumario:In Spain, diarrhea remains a major cause of illness among infants and young children. To determine the prevalence of rotavirus genotypes and temporal and geographic differences in strain distribution, a structured surveillance study of hospitalized children <5 years of age with diarrhea was initiated in different regions of Spain during 2005. Rotavirus was detected alone in samples from 362 (55.2%) samples and as a coinfection with other viruses in 41 samples (6.3%). Enteropathogenic bacterial agents were detected in 4.9% of samples; astrovirus and norovirus RNA was detected in 3.2% and 12.0% samples, respectively; and adenovirus antigen was detected in 1.8% samples. Including mixed infections, the most predominant G type was G9 (50.6%), followed by G3 (33.0%) and G1 (20.2%). Infection with multiple rotavirus strains was detected in >11.4% of the samples studied during 2005.