Surgical Principles of Primary Retroperitoneal Sarcoma in the Era of Personalized Treatment

Surgery is the key treatment in retroperitoneal sarcoma (RPS), as completeness of resection is the most important prognostic factor related to treatment. Compartmental surgery/frontline extended approach is based on soft-tissue sarcoma surgical principles, and involves resecting adjacent viscera to...

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Detalles Bibliográficos
Autores: Munoz, Paula|||0000-0002-6334-3014, Bretcha-Boix, Pedro|||0000-0002-0530-2142, Artigas Raventos, Vicens|||0000-0002-2874-2490, Asencio, Jose Manuel|||0000-0002-7533-5513
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:292233
Acceso en línea:https://ddd.uab.cat/record/292233
https://dx.doi.org/urn:doi:10.3390/cancers14174091
Access Level:acceso abierto
Palabra clave:Compartmental surgery
Leiomyosarcoma
Liposarcoma
Retroperitoneal sarcoma
Solitary fibrous tumor
Descripción
Sumario:Surgery is the key treatment in retroperitoneal sarcoma (RPS), as completeness of resection is the most important prognostic factor related to treatment. Compartmental surgery/frontline extended approach is based on soft-tissue sarcoma surgical principles, and involves resecting adjacent viscera to achieve a wide negative margin. This extended approach is associated with improved local control and survival. This surgery must be tailored to tumor histology, tumor localization, and patient performance status. We herein present a review of compartmental surgery principles, covering the oncological and technical basis, and describing the tailored approach to each tumor subtype and localization in the retroperitoneum.