Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study
Rathke’s cleft cyst; Transsphenoidal surgery; Visual impairment
| Autores: | , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Departament de Salut de la Generalitat de Catalunya (DS) |
| Repositorio: | Scientia. Dipòsit d'Informació Digital del Departament de Salut |
| OAI Identifier: | oai:scientiasalut.gencat.cat:11351/11676 |
| Acceso en línea: | https://hdl.handle.net/11351/11676 |
| Access Level: | acceso abierto |
| Palabra clave: | Avaluació de resultats (Assistència sanitària) Quistos Sistema nerviós central - Càncer - Cirurgia Hipòfisi ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome DISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Central Nervous System Cysts Other subheadings::Other subheadings::Other subheadings::/surgery DISEASES::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Pituitary Neoplasms TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::quistes del sistema nervioso central Otros calificadores::Otros calificadores::Otros calificadores::/cirugía ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de las glándulas endocrinas::neoplasias hipofisarias |
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| dc.title.none.fl_str_mv |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| title |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| spellingShingle |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study Menéndez Torre, Edelmiro Avaluació de resultats (Assistència sanitària) Quistos Sistema nerviós central - Càncer - Cirurgia Hipòfisi ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome DISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Central Nervous System Cysts Other subheadings::Other subheadings::Other subheadings::/surgery DISEASES::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Pituitary Neoplasms TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::quistes del sistema nervioso central Otros calificadores::Otros calificadores::Otros calificadores::/cirugía ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de las glándulas endocrinas::neoplasias hipofisarias |
| title_short |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| title_full |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| title_fullStr |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| title_full_unstemmed |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| title_sort |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study |
| dc.creator.none.fl_str_mv |
Menéndez Torre, Edelmiro Gutiérrez-Hurtado, Alba Ollero, María Dolores Irigaray, Ana Martín, Patricia Parra Ramírez, Paola Biagetti, Betina |
| author |
Menéndez Torre, Edelmiro |
| author_facet |
Menéndez Torre, Edelmiro Gutiérrez-Hurtado, Alba Ollero, María Dolores Irigaray, Ana Martín, Patricia Parra Ramírez, Paola Biagetti, Betina |
| author_role |
author |
| author2 |
Gutiérrez-Hurtado, Alba Ollero, María Dolores Irigaray, Ana Martín, Patricia Parra Ramírez, Paola Biagetti, Betina |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Institut Català de la Salut [Menéndez-Torre EL] Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Oviedo, Spain. Grupo ENDO, Instituto de Investigación Biomédica del Principado de Asturias (ISPA), Oviedo, Spain. Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain. [Gutiérrez-Hurtado A] Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Oviedo, Spain. [Ollero MD, Irigaray A] Department of Endocrinology and Nutrition, Hospital Universitario de Navarra, Pamplona, Spain. [Martín P, Parra P] Department of Endocrinology and Nutrition, Hospital Universitario La Paz, Madrid, Spain. [Biagetti B] Servei d’Endocrinologia i Nutrició, Vall d’Hebron Hospital Universitari, Barcelona, Spain Vall d'Hebron Barcelona Hospital Campus |
| dc.subject.none.fl_str_mv |
Avaluació de resultats (Assistència sanitària) Quistos Sistema nerviós central - Càncer - Cirurgia Hipòfisi ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome DISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Central Nervous System Cysts Other subheadings::Other subheadings::Other subheadings::/surgery DISEASES::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Pituitary Neoplasms TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::quistes del sistema nervioso central Otros calificadores::Otros calificadores::Otros calificadores::/cirugía ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de las glándulas endocrinas::neoplasias hipofisarias |
| topic |
Avaluació de resultats (Assistència sanitària) Quistos Sistema nerviós central - Càncer - Cirurgia Hipòfisi ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome DISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Central Nervous System Cysts Other subheadings::Other subheadings::Other subheadings::/surgery DISEASES::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Pituitary Neoplasms TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::quistes del sistema nervioso central Otros calificadores::Otros calificadores::Otros calificadores::/cirugía ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de las glándulas endocrinas::neoplasias hipofisarias |
| description |
Rathke’s cleft cyst; Transsphenoidal surgery; Visual impairment |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024 2024 2024 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/11351/11676 |
| url |
https://hdl.handle.net/11351/11676 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Frontiers in Endocrinology;15 https://doi.org/10.3389/fendo.2024.1413810 |
| dc.rights.none.fl_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Frontiers Media |
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Frontiers Media |
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Scientia reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut instname:Departament de Salut de la Generalitat de Catalunya (DS) |
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Departament de Salut de la Generalitat de Catalunya (DS) |
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Scientia. Dipòsit d'Informació Digital del Departament de Salut |
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Scientia. Dipòsit d'Informació Digital del Departament de Salut |
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1869403593056976896 |
| spelling |
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter studyMenéndez Torre, EdelmiroGutiérrez-Hurtado, AlbaOllero, María DoloresIrigaray, AnaMartín, PatriciaParra Ramírez, PaolaBiagetti, BetinaAvaluació de resultats (Assistència sanitària)QuistosSistema nerviós central - Càncer - CirurgiaHipòfisiANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment OutcomeDISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Central Nervous System CystsOther subheadings::Other subheadings::Other subheadings::/surgeryDISEASES::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Pituitary NeoplasmsTÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamientoENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::quistes del sistema nervioso centralOtros calificadores::Otros calificadores::Otros calificadores::/cirugíaENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de las glándulas endocrinas::neoplasias hipofisariasRathke’s cleft cyst; Transsphenoidal surgery; Visual impairmentQuiste de hendidura de Rathke; Hipófisis; Cirugía transesfenoidalQuist de fendedura de Rathke; Hipòfisi; Cirurgia transesfenoïdalRathke’s cleft cysts (RCC) are a common type of lesion found in the sellar or suprasellar area. They are usually monitored clinically, but in some cases, surgery may be required. However, their natural progression is not yet well understood, and the outcomes of surgery are uncertain. The objective of this study is to evaluate the natural history of Rathke’s cleft cysts in patients who are clinically monitored without treatment, and to determine the outcomes of surgery and the incidence of recurrences over time. Design and patients: National multicentric study of patients diagnosed of Rathke’s cleft cyst (RCC- Spain) from 2000 onwards and followed in 15 tertiary centers of Spain. A total of 177 patients diagnosed of RCC followed for 67.3 months (6–215) and 88 patients who underwent surgery, (81 patients underwent immediate surgery after diagnosis and 7 later for subsequent growth) followed for 68.8 months (3–235). Results: The cyst size remained stable or decreased in 73.5% (133) of the patients. Only 44 patients (24.3%) experienced a cyst increase and 9 of them (5.1%) experienced an increase greater than 3 mm. In most of the patients who underwent surgery headaches and visual alterations improved, recurrence was observed in 8 (9.1%) after a median time of 96 months, and no predictors of recurrence were discovered. Conclusions: Rathke’s cleft cysts without initial compressive symptoms have a low probability of growth, so conservative management is recommended. Patients who undergo transsphenoidal surgery experience rapid clinical improvement, and recurrences are infrequent. However, they can occur after a long period of time, although no predictors of recurrence have been identified.Frontiers MediaInstitut Català de la Salut[Menéndez-Torre EL] Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Oviedo, Spain. Grupo ENDO, Instituto de Investigación Biomédica del Principado de Asturias (ISPA), Oviedo, Spain. Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain. [Gutiérrez-Hurtado A] Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Oviedo, Spain. [Ollero MD, Irigaray A] Department of Endocrinology and Nutrition, Hospital Universitario de Navarra, Pamplona, Spain. [Martín P, Parra P] Department of Endocrinology and Nutrition, Hospital Universitario La Paz, Madrid, Spain. [Biagetti B] Servei d’Endocrinologia i Nutrició, Vall d’Hebron Hospital Universitari, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202420242024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/11676Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésFrontiers in Endocrinology;15https://doi.org/10.3389/fendo.2024.1413810Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/116762026-06-12T09:38:37Z |
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15.812429 |