Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication

Drug-drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highlights from the 'First Workshop on Pharmacology a...

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Autores: Bellet Ezquerra, Meritxell, Ahmad, Faten, Villanueva, Rafael, Valdivia, Carolina, Palomino Doza, Julián, Ruiz, Ada, Gonzalez-Farre, Xavier, Adrover, Encarna, Azaro, Analía, Valls Margarit, Maria, Parra, Josep Lluís, Aguilar Company, Juan, Vidal Losada, Maria Jesús, Martin, Anastasi, Gavilá, Joaquín, Escrivá de Romaní, Santiago, Perelló, Antonia, Hernando, Cristina, Lahuerta, Ainhara, Zamora, Pilar, Reyes, Victoria, Alcalde, María, Masanas, Helena, Celiz, Pamela, Ruiz, Isabel, Gil Gil, Miguel, Seguí, Miquel A., Peña, Lorena de la
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/171556
Acceso en línea:https://hdl.handle.net/2445/171556
Access Level:acceso abierto
Palabra clave:Càncer de mama
Oncologia
Breast cancer
Oncology
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spelling Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medicationBellet Ezquerra, MeritxellAhmad, FatenVillanueva, RafaelValdivia, CarolinaPalomino Doza, JuliánRuiz, AdaGonzalez-Farre, XavierAdrover, EncarnaAzaro, AnalíaValls Margarit, MariaParra, Josep LluísAguilar Company, JuanVidal Losada, Maria JesúsMartin, AnastasiGavilá, JoaquínEscrivá de Romaní, SantiagoPerelló, AntoniaHernando, CristinaLahuerta, AinharaZamora, PilarReyes, VictoriaAlcalde, MaríaMasanas, HelenaCeliz, PamelaRuiz, IsabelGil Gil, MiguelSeguí, Miquel A.Peña, Lorena de laCàncer de mamaOncologiaBreast cancerOncologyDrug-drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highlights from the 'First Workshop on Pharmacology and Management of CDK4/6 Inhibitors: Consensus about Concomitant Medications'. The article is structured into two modules. The educational module includes background information regarding drug metabolism, corrected QT (QTc) interval abnormalities, management of psychotropic drugs and a comprehensive review of selected adverse effects of palbociclib and ribociclib. The collaborative module presents the conclusions of the five working groups, each of which comprised five experts from different fields. From these conclusions positive lists of drugs for treating common comorbid conditions that can be safely administered concomitantly with palbociclib and/or ribociclib were developed.Sage Publications Ltd.2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/171556Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1177/1758835919833867Therapeutic Advances in Medical Oncology, 2019, vol. 11https://doi.org/10.1177/1758835919833867cc by-nc (c) Bellet et al., 2019http://creativecommons.org/licenses/by-nc/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1715562026-05-27T06:46:51Z
dc.title.none.fl_str_mv Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
title Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
spellingShingle Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
Bellet Ezquerra, Meritxell
Càncer de mama
Oncologia
Breast cancer
Oncology
title_short Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
title_full Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
title_fullStr Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
title_full_unstemmed Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
title_sort Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication
dc.creator.none.fl_str_mv Bellet Ezquerra, Meritxell
Ahmad, Faten
Villanueva, Rafael
Valdivia, Carolina
Palomino Doza, Julián
Ruiz, Ada
Gonzalez-Farre, Xavier
Adrover, Encarna
Azaro, Analía
Valls Margarit, Maria
Parra, Josep Lluís
Aguilar Company, Juan
Vidal Losada, Maria Jesús
Martin, Anastasi
Gavilá, Joaquín
Escrivá de Romaní, Santiago
Perelló, Antonia
Hernando, Cristina
Lahuerta, Ainhara
Zamora, Pilar
Reyes, Victoria
Alcalde, María
Masanas, Helena
Celiz, Pamela
Ruiz, Isabel
Gil Gil, Miguel
Seguí, Miquel A.
Peña, Lorena de la
author Bellet Ezquerra, Meritxell
author_facet Bellet Ezquerra, Meritxell
Ahmad, Faten
Villanueva, Rafael
Valdivia, Carolina
Palomino Doza, Julián
Ruiz, Ada
Gonzalez-Farre, Xavier
Adrover, Encarna
Azaro, Analía
Valls Margarit, Maria
Parra, Josep Lluís
Aguilar Company, Juan
Vidal Losada, Maria Jesús
Martin, Anastasi
Gavilá, Joaquín
Escrivá de Romaní, Santiago
Perelló, Antonia
Hernando, Cristina
Lahuerta, Ainhara
Zamora, Pilar
Reyes, Victoria
Alcalde, María
Masanas, Helena
Celiz, Pamela
Ruiz, Isabel
Gil Gil, Miguel
Seguí, Miquel A.
Peña, Lorena de la
author_role author
author2 Ahmad, Faten
Villanueva, Rafael
Valdivia, Carolina
Palomino Doza, Julián
Ruiz, Ada
Gonzalez-Farre, Xavier
Adrover, Encarna
Azaro, Analía
Valls Margarit, Maria
Parra, Josep Lluís
Aguilar Company, Juan
Vidal Losada, Maria Jesús
Martin, Anastasi
Gavilá, Joaquín
Escrivá de Romaní, Santiago
Perelló, Antonia
Hernando, Cristina
Lahuerta, Ainhara
Zamora, Pilar
Reyes, Victoria
Alcalde, María
Masanas, Helena
Celiz, Pamela
Ruiz, Isabel
Gil Gil, Miguel
Seguí, Miquel A.
Peña, Lorena de la
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Càncer de mama
Oncologia
Breast cancer
Oncology
topic Càncer de mama
Oncologia
Breast cancer
Oncology
description Drug-drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highlights from the 'First Workshop on Pharmacology and Management of CDK4/6 Inhibitors: Consensus about Concomitant Medications'. The article is structured into two modules. The educational module includes background information regarding drug metabolism, corrected QT (QTc) interval abnormalities, management of psychotropic drugs and a comprehensive review of selected adverse effects of palbociclib and ribociclib. The collaborative module presents the conclusions of the five working groups, each of which comprised five experts from different fields. From these conclusions positive lists of drugs for treating common comorbid conditions that can be safely administered concomitantly with palbociclib and/or ribociclib were developed.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/171556
url https://hdl.handle.net/2445/171556
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1177/1758835919833867
Therapeutic Advances in Medical Oncology, 2019, vol. 11
https://doi.org/10.1177/1758835919833867
dc.rights.none.fl_str_mv cc by-nc (c) Bellet et al., 2019
http://creativecommons.org/licenses/by-nc/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by-nc (c) Bellet et al., 2019
http://creativecommons.org/licenses/by-nc/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sage Publications Ltd.
publisher.none.fl_str_mv Sage Publications Ltd.
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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