The microbiological transformation of 14$,19-dihydroxy-ent-kaur-15-ene by Gibberella fujikuroi

The biotransformation by the fungus Gibberella fujikuroi of the diterpene ent-14$,19-dihydroxy-kaur-15-ene gave ent-14$,15$.19-trihydroxy-kaur-16-ene, ent-14$,15$19-trihydroxy-11$,16$-epoxy-kaurane, ent-15$16$-epoxy-7$,14$,19-trihydroxy-kaurane, ent-7$,14$,19-trihydroxy-kaur-15-ene, ent7$,14$-dihydr...

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Bibliographic Details
Authors: Fraga, Braulio M., García-Tellado, Fernando, González, Pedro, Hernández, Melchor G.
Format: article
Publication Date:1993
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/21677
Online Access:http://hdl.handle.net/10261/21677
Access Level:Open access
Keyword:Gibberella fujikuroi
Microbiological transformations
Diterpenes
Isokaurene
ent-14$,19-dihyudroxy-kaur-15-ene
Description
Summary:The biotransformation by the fungus Gibberella fujikuroi of the diterpene ent-14$,19-dihydroxy-kaur-15-ene gave ent-14$,15$.19-trihydroxy-kaur-16-ene, ent-14$,15$19-trihydroxy-11$,16$-epoxy-kaurane, ent-15$16$-epoxy-7$,14$,19-trihydroxy-kaurane, ent-7$,14$,19-trihydroxy-kaur-15-ene, ent7$,14$-dihydroxy-15$,16$-epoxy-kauran-19-oic acid, ent-7$,14$-dihydroxy-kaur-15-en-19-oic acid, ent-6$,7$,14$-trihydroxy-kaur-15-en-19-oic acid, ent-6$,7$,14$,15$-tetrahydroxy-kaur-16-en-19-oic acid and ent-15$,16$-epoxy-6$,7$,14$-trihydroxy-kauran-19-oic acid. The 14$-hydroxy-15$,16$-epoxy-GA$ was the sole gibberellin obtained in this incubation.