Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY)
Background: To evaluate the impact of applying alternative diagnostic criteria for gestational diabetes mellitus (GDM) during the COVID-19 pandemic on GDM prevalence, obstetrical and perinatal outcomes, and costs, as compared to the standard diagnostic method. Methods: A cohort of pregnant individua...
| Autores: | , , , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Recursos: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:307644 |
| Acesso em linha: | https://ddd.uab.cat/record/307644 https://dx.doi.org/urn:doi:10.3390/diagnostics15020189 |
| Access Level: | acceso abierto |
| Palavra-chave: | COVID-19 OGTT O'Sullivan Gestational diabetes Glucose level Glycated hemoglobin Large for gestational age (LGA) Macrosomia Neonatal hypoglycemia Screening |
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Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) An Observational Cohort Study |
| title |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| spellingShingle |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) Casellas Comallonga, Alba|||0000-0003-0203-4733 COVID-19 OGTT O'Sullivan Gestational diabetes Glucose level Glycated hemoglobin Large for gestational age (LGA) Macrosomia Neonatal hypoglycemia Screening |
| title_short |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| title_full |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| title_fullStr |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| title_full_unstemmed |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| title_sort |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY) |
| dc.creator.none.fl_str_mv |
Casellas Comallonga, Alba|||0000-0003-0203-4733 Martínez, C. Amigó, Judit|||0000-0003-2407-1906 Ferrer Costa, Roser|||0000-0002-8925-3172 Martí, Laia Merced, C. Medina Mallen, Maria del Carmen|||0000-0002-1219-5947 Molinero, I. Calveiro, M. Maroto, Anna|||0000-0003-3225-9095 del Barco, Ester|||0000-0002-1484-9027 Carreras Moratonas, Elena|||0000-0003-3471-7248 Goya, M.|||0000-0003-4001-2017 |
| author |
Casellas Comallonga, Alba|||0000-0003-0203-4733 |
| author_facet |
Casellas Comallonga, Alba|||0000-0003-0203-4733 Martínez, C. Amigó, Judit|||0000-0003-2407-1906 Ferrer Costa, Roser|||0000-0002-8925-3172 Martí, Laia Merced, C. Medina Mallen, Maria del Carmen|||0000-0002-1219-5947 Molinero, I. Calveiro, M. Maroto, Anna|||0000-0003-3225-9095 del Barco, Ester|||0000-0002-1484-9027 Carreras Moratonas, Elena|||0000-0003-3471-7248 Goya, M.|||0000-0003-4001-2017 |
| author_role |
author |
| author2 |
Martínez, C. Amigó, Judit|||0000-0003-2407-1906 Ferrer Costa, Roser|||0000-0002-8925-3172 Martí, Laia Merced, C. Medina Mallen, Maria del Carmen|||0000-0002-1219-5947 Molinero, I. Calveiro, M. Maroto, Anna|||0000-0003-3225-9095 del Barco, Ester|||0000-0002-1484-9027 Carreras Moratonas, Elena|||0000-0003-3471-7248 Goya, M.|||0000-0003-4001-2017 |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
COVID-19 OGTT O'Sullivan Gestational diabetes Glucose level Glycated hemoglobin Large for gestational age (LGA) Macrosomia Neonatal hypoglycemia Screening |
| topic |
COVID-19 OGTT O'Sullivan Gestational diabetes Glucose level Glycated hemoglobin Large for gestational age (LGA) Macrosomia Neonatal hypoglycemia Screening |
| description |
Background: To evaluate the impact of applying alternative diagnostic criteria for gestational diabetes mellitus (GDM) during the COVID-19 pandemic on GDM prevalence, obstetrical and perinatal outcomes, and costs, as compared to the standard diagnostic method. Methods: A cohort of pregnant individuals undergoing GMD screening with the alternative GDM method, which uses plasma glucose (fasting or non-fasting) and HbA1c, was compared with a cohort of pregnant individuals undergoing the standard GDM screening method. Both cohorts were obtained from six hospitals across Catalonia, Spain, from April 2020 to April 2022. The primary outcome was large for gestational age rate at birth. The secondary outcomes were composite adverse outcomes, including pregnancy complications, delivery complications, and neonatal complications. The cost differences between screening methods were also evaluated. A similar analysis was performed in the subgroup diagnosed with GDM. Results: Data were collected from 1543 pregnant individuals in the standard screening group and 2197 in the alternative screening group. The standard screening group had a higher GDM diagnostic rate than the alternative screening group (10.8% vs. 6.9%, respectively; p < 0.0001). The primary outcome (large for gestational age rate) was similar between groups: 200/1543 (13.0%) vs. 303/2197 (13.8%). The adjusted OR for this outcome was 1.74 (95% CI: 0.74-4.10). An adjusted analysis showed no differences between groups in the composite adverse outcomes for pregnancy complications (OR: 1.11; 95% CI: 0.91-1.36), delivery complications (OR: 0.95; 95% CI: 0.75-1.19), and neonatal complications (OR: 1.28; 95% CI: 0.94-1.75). Among individuals diagnosed with GDM, the large for gestational age rate was similar between groups: 13/166 (7.8%) vs. 15/151 (9.9%). The OR adjusted for this outcome was 1.24 (95% CI: 0.51-3.09). An adjusted analysis showed no differences in the composite adverse outcomes for pregnancy complications (OR: 1.57; 95% CI: 0.84-2.98), delivery complications (OR: 1.21; 95% CI: 0.63-2.35), and neonatal complications (OR: 1.35; 95% CI: 0.61-3.04). The mean cost (which included expenses for consumables, equipment, and personnel) of the alternative screening method was 46.0 euros (22.3 SD), as compared to 85.6 euros (67.5 SD) for the standard screening method. Conclusions: In this Spanish population during the COVID-19 pandemic, GDM prevalence was lower in the alternative screening group than in the standard screening group. After adjusting for GDM risk factors, outcomes related to obstetrics, delivery, and neonatal complications were comparable between both groups. Finally, the alternative screening method was cheaper than the standard screening method. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2 2025-01-01 2025 2025-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/307644 https://dx.doi.org/urn:doi:10.3390/diagnostics15020189 |
| url |
https://ddd.uab.cat/record/307644 https://dx.doi.org/urn:doi:10.3390/diagnostics15020189 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Universitat Autònoma de Barcelona |
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Dipòsit Digital de Documents de la UAB |
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Dipòsit Digital de Documents de la UAB |
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1869403533561823232 |
| spelling |
Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY)An Observational Cohort StudyCasellas Comallonga, Alba|||0000-0003-0203-4733Martínez, C.Amigó, Judit|||0000-0003-2407-1906Ferrer Costa, Roser|||0000-0002-8925-3172Martí, LaiaMerced, C.Medina Mallen, Maria del Carmen|||0000-0002-1219-5947Molinero, I.Calveiro, M.Maroto, Anna|||0000-0003-3225-9095del Barco, Ester|||0000-0002-1484-9027Carreras Moratonas, Elena|||0000-0003-3471-7248Goya, M.|||0000-0003-4001-2017COVID-19OGTTO'SullivanGestational diabetesGlucose levelGlycated hemoglobinLarge for gestational age (LGA)MacrosomiaNeonatal hypoglycemiaScreeningBackground: To evaluate the impact of applying alternative diagnostic criteria for gestational diabetes mellitus (GDM) during the COVID-19 pandemic on GDM prevalence, obstetrical and perinatal outcomes, and costs, as compared to the standard diagnostic method. Methods: A cohort of pregnant individuals undergoing GMD screening with the alternative GDM method, which uses plasma glucose (fasting or non-fasting) and HbA1c, was compared with a cohort of pregnant individuals undergoing the standard GDM screening method. Both cohorts were obtained from six hospitals across Catalonia, Spain, from April 2020 to April 2022. The primary outcome was large for gestational age rate at birth. The secondary outcomes were composite adverse outcomes, including pregnancy complications, delivery complications, and neonatal complications. The cost differences between screening methods were also evaluated. A similar analysis was performed in the subgroup diagnosed with GDM. Results: Data were collected from 1543 pregnant individuals in the standard screening group and 2197 in the alternative screening group. The standard screening group had a higher GDM diagnostic rate than the alternative screening group (10.8% vs. 6.9%, respectively; p < 0.0001). The primary outcome (large for gestational age rate) was similar between groups: 200/1543 (13.0%) vs. 303/2197 (13.8%). The adjusted OR for this outcome was 1.74 (95% CI: 0.74-4.10). An adjusted analysis showed no differences between groups in the composite adverse outcomes for pregnancy complications (OR: 1.11; 95% CI: 0.91-1.36), delivery complications (OR: 0.95; 95% CI: 0.75-1.19), and neonatal complications (OR: 1.28; 95% CI: 0.94-1.75). Among individuals diagnosed with GDM, the large for gestational age rate was similar between groups: 13/166 (7.8%) vs. 15/151 (9.9%). The OR adjusted for this outcome was 1.24 (95% CI: 0.51-3.09). An adjusted analysis showed no differences in the composite adverse outcomes for pregnancy complications (OR: 1.57; 95% CI: 0.84-2.98), delivery complications (OR: 1.21; 95% CI: 0.63-2.35), and neonatal complications (OR: 1.35; 95% CI: 0.61-3.04). The mean cost (which included expenses for consumables, equipment, and personnel) of the alternative screening method was 46.0 euros (22.3 SD), as compared to 85.6 euros (67.5 SD) for the standard screening method. Conclusions: In this Spanish population during the COVID-19 pandemic, GDM prevalence was lower in the alternative screening group than in the standard screening group. After adjusting for GDM risk factors, outcomes related to obstetrics, delivery, and neonatal complications were comparable between both groups. Finally, the alternative screening method was cheaper than the standard screening method.Universitat Autònoma de Barcelona 22025-01-0120252025-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/307644https://dx.doi.org/urn:doi:10.3390/diagnostics15020189reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3076442026-06-06T12:50:31Z |
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15,811543 |