Biocompatible 3D printed yttria-stabilized zirconia parts using direct ink writing

Metals such as titanium or Cr-Co alloys have been the most widely used materials in biomedical applications that requirehigh mechanical properties, like implants. However, these materials present the disadvantage of releasing ion metals intothe body. As an alternative, prostheses made of ceramic mat...

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Detalhes bibliográficos
Autores: Buj Corral, Irene, Sanz Fraile, Héctor, Tejo-Otero, Aitor, Vidal, Daniel, Padilla Sanchez, Jose Antonio, Xuriguera Martín, María Elena, Otero Diaz, Jorge
Tipo de documento: artigo
Estado:Versión aceptada para publicación
Data de publicação:2024
País:España
Recursos:Universidad de Barcelona
Repositório:Dipòsit Digital de la UB
OAI Identifier:oai:dnet:ubarcelona__::20bb14c72d1284c17c64936c08941eea
Acesso em linha:https://hdl.handle.net/2445/228552
Access Level:Acceso aberto
Palavra-chave:Materials biomèdics
Materials refractaris
Biomedical materials
Refractory materials
Descrição
Resumo:Metals such as titanium or Cr-Co alloys have been the most widely used materials in biomedical applications that requirehigh mechanical properties, like implants. However, these materials present the disadvantage of releasing ion metals intothe body. As an alternative, prostheses made of ceramic materials have been developed, as they produce less debris andhave better durability. The aim of the present work is to test the biocompatibility of 3D-printed yttria-stabilized zirconia</p><p>parts by culturing human bone-marrow-derived mesenchymal stem cells. Two different scaffols were 3D printed having a</p><p>liner infill pattern, with 80 % and 95 % infill rate respectively. Results on surface roughness and biocompatibility tests</p><p>confirmed that 3 mol % yttria-stabilized zirconia is a highly promising material as it presented high biocompatibility. In adition,</p><p>similar results were obtained with or without the use of a type I collagen coating., which suggest that coating couldbe avoided when on zirconia substraes.