Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome
BACKGROUND Young (<18 years of age) patients with Brugada syndrome (BrS) are often under-represented in BrS studies and their management, especially related to syncopal episodes, remains unclear. OBJECTIVES This study sought to describe the arrhythmia prevalence among young patients with BrS unde...
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Fundació Sant Joan de Déu |
| Repositorio: | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| OAI Identifier: | oai:fsjd.fundanetsuite.com:p26657 |
| Acceso en línea: | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=26657 |
| Access Level: | acceso abierto |
| Palabra clave: | adolescent atrial arrhythmias bradyarrhythmias Brugada syndrome implantable loop recorder pediatric rhythm monitoring sudden cardiac death syncope ventricular arrhythmias young |
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Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada SyndromeBergonti MCiconte GCruzalegui Gomez JCrotti LArbelo ECasella MSaenen JRossi APannone LMartinez-Barrios ECompagnucci PRusso VBerne PVan Leuven OBoccellino AMarcon LDagradi FLandra FÖzkartal TComune AConti SRibatti VCampuzano OBrugada Pde Asmundis CBrugada JPappone CTondo CSchwartz PJAuricchio ASarquella-Brugada GConte Gadolescentatrial arrhythmiasbradyarrhythmiasBrugada syndromeimplantable loop recorderpediatricrhythm monitoringsudden cardiac deathsyncopeventricular arrhythmiasyoungBACKGROUND Young (<18 years of age) patients with Brugada syndrome (BrS) are often under-represented in BrS studies and their management, especially related to syncopal episodes, remains unclear. OBJECTIVES This study sought to describe the arrhythmia prevalence among young patients with BrS undergoing continuous rhythm monitoring by implantable loop recorder (ILR) and to assess the etiology behind syncope of undetermined origin. METHODS A total of 147 patients with BrS with ILR were enrolled in 12 international centers and divided into pediatric (age <12 years; n = 77, 52%) and adolescents (age 13-18 years; n = 70, 48%). RESULTS Mean age was 11.3 years, 53 patients (36.1%) were female, and 31 (21.1%) had spontaneous type 1 electrocardiograms. Over a median follow-up of 3.6 years (Q1-Q3: 1.6-4.8 years), an arrhythmic event was recorded in 33 patients (22.4%), mainly of nonventricular origin: 15 atrial (10.2%) and 16 bradyarrhythmic events (10.9%). Ventricular arrhythmias occurred in 4 patients, all with spontaneous BrS, and were fever-related in one-half. Among all patients with recurrence of syncope during follow-up, true arrhythmic syncope was documented in 5 (17.8%), and it was due to bradyarrhythmias or atrial arrhythmias in 3 cases (60%). CONCLUSIONS Continuous rhythm monitoring with ILRs in young patients with BrS detects a broad range of arrhythmias. Ventricular arrhythmias occur predominantly in patients with spontaneous type 1 electrocardiograms and during fever. Despite the young age, bradyarrhythmias and atrial arrhythmias are frequent and represent the cause of arrhythmic syncope in 60% of patients. Young patients with BrS with syncope of undetermined origin may benefit from ILR implant. (c) 2024 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).ELSEVIER SCIENCE INC2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=26657JACC-JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYISSN: 07351097ISSNe: 15583597reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p266572026-05-27T12:37:41Z |
| dc.title.none.fl_str_mv |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| title |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| spellingShingle |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome Bergonti M adolescent atrial arrhythmias bradyarrhythmias Brugada syndrome implantable loop recorder pediatric rhythm monitoring sudden cardiac death syncope ventricular arrhythmias young |
| title_short |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| title_full |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| title_fullStr |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| title_full_unstemmed |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| title_sort |
Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome |
| dc.creator.none.fl_str_mv |
Bergonti M Ciconte G Cruzalegui Gomez J Crotti L Arbelo E Casella M Saenen J Rossi A Pannone L Martinez-Barrios E Compagnucci P Russo V Berne P Van Leuven O Boccellino A Marcon L Dagradi F Landra F Özkartal T Comune A Conti S Ribatti V Campuzano O Brugada P de Asmundis C Brugada J Pappone C Tondo C Schwartz PJ Auricchio A Sarquella-Brugada G Conte G |
| author |
Bergonti M |
| author_facet |
Bergonti M Ciconte G Cruzalegui Gomez J Crotti L Arbelo E Casella M Saenen J Rossi A Pannone L Martinez-Barrios E Compagnucci P Russo V Berne P Van Leuven O Boccellino A Marcon L Dagradi F Landra F Özkartal T Comune A Conti S Ribatti V Campuzano O Brugada P de Asmundis C Brugada J Pappone C Tondo C Schwartz PJ Auricchio A Sarquella-Brugada G Conte G |
| author_role |
author |
| author2 |
Ciconte G Cruzalegui Gomez J Crotti L Arbelo E Casella M Saenen J Rossi A Pannone L Martinez-Barrios E Compagnucci P Russo V Berne P Van Leuven O Boccellino A Marcon L Dagradi F Landra F Özkartal T Comune A Conti S Ribatti V Campuzano O Brugada P de Asmundis C Brugada J Pappone C Tondo C Schwartz PJ Auricchio A Sarquella-Brugada G Conte G |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
adolescent atrial arrhythmias bradyarrhythmias Brugada syndrome implantable loop recorder pediatric rhythm monitoring sudden cardiac death syncope ventricular arrhythmias young |
| topic |
adolescent atrial arrhythmias bradyarrhythmias Brugada syndrome implantable loop recorder pediatric rhythm monitoring sudden cardiac death syncope ventricular arrhythmias young |
| description |
BACKGROUND Young (<18 years of age) patients with Brugada syndrome (BrS) are often under-represented in BrS studies and their management, especially related to syncopal episodes, remains unclear. OBJECTIVES This study sought to describe the arrhythmia prevalence among young patients with BrS undergoing continuous rhythm monitoring by implantable loop recorder (ILR) and to assess the etiology behind syncope of undetermined origin. METHODS A total of 147 patients with BrS with ILR were enrolled in 12 international centers and divided into pediatric (age <12 years; n = 77, 52%) and adolescents (age 13-18 years; n = 70, 48%). RESULTS Mean age was 11.3 years, 53 patients (36.1%) were female, and 31 (21.1%) had spontaneous type 1 electrocardiograms. Over a median follow-up of 3.6 years (Q1-Q3: 1.6-4.8 years), an arrhythmic event was recorded in 33 patients (22.4%), mainly of nonventricular origin: 15 atrial (10.2%) and 16 bradyarrhythmic events (10.9%). Ventricular arrhythmias occurred in 4 patients, all with spontaneous BrS, and were fever-related in one-half. Among all patients with recurrence of syncope during follow-up, true arrhythmic syncope was documented in 5 (17.8%), and it was due to bradyarrhythmias or atrial arrhythmias in 3 cases (60%). CONCLUSIONS Continuous rhythm monitoring with ILRs in young patients with BrS detects a broad range of arrhythmias. Ventricular arrhythmias occur predominantly in patients with spontaneous type 1 electrocardiograms and during fever. Despite the young age, bradyarrhythmias and atrial arrhythmias are frequent and represent the cause of arrhythmic syncope in 60% of patients. Young patients with BrS with syncope of undetermined origin may benefit from ILR implant. (c) 2024 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=26657 |
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https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=26657 |
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Inglés |
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Inglés |
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info:eu-repo/semantics/openAccess |
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openAccess |
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ELSEVIER SCIENCE INC |
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ELSEVIER SCIENCE INC |
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JACC-JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ISSN: 07351097 ISSNe: 15583597 reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname:Fundació Sant Joan de Déu |
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r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
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r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
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