Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials

The discovery of new structure-activity relationships represents a promising avenue for designing innovative materials and understanding the principles governing biological processes. Nevertheless, advances in this field have been limited by current methodologies used in the preparation of polymeric...

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Detalhes bibliográficos
Autor: Delgado González, Bruno
Formato: tesis doctoral
Fecha de publicación:2024
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/37798
Acesso em linha:https://hdl.handle.net/10347/37798
Access Level:acceso abierto
Palavra-chave:Boronic Acid
Dynamic Covalent Chemistry
Bioactive Polymeric Materials
230403 Polímeros compuestos
230408 Macromoléculas
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spelling Dynamic Covalent Boronate Chemistry for Bioactive Polymeric MaterialsDelgado González, BrunoBoronic AcidDynamic Covalent ChemistryBioactive Polymeric Materials230403 Polímeros compuestos230408 MacromoléculasThe discovery of new structure-activity relationships represents a promising avenue for designing innovative materials and understanding the principles governing biological processes. Nevertheless, advances in this field have been limited by current methodologies used in the preparation of polymeric structures. In this context, dynamic covalent chemistry emerges as a valuable tool for developing highly adaptable materials. This thesis aims to bridge these two concepts. By employing a dendrimer and a dendritic block copolymer as bricks, and the fast-forming and strong boronate bond as cement, a novel technology has been developed for constructing bioactive materials with implications in drug delivery, gene therapy, and the fabrication of artificial cells.Fernández Megía, EduardoUniversidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)20242024-01-0120242024-01-01doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/10347/37798reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/377982026-06-15T12:47:27Z
dc.title.none.fl_str_mv Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
title Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
spellingShingle Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
Delgado González, Bruno
Boronic Acid
Dynamic Covalent Chemistry
Bioactive Polymeric Materials
230403 Polímeros compuestos
230408 Macromoléculas
title_short Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
title_full Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
title_fullStr Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
title_full_unstemmed Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
title_sort Dynamic Covalent Boronate Chemistry for Bioactive Polymeric Materials
dc.creator.none.fl_str_mv Delgado González, Bruno
author Delgado González, Bruno
author_facet Delgado González, Bruno
author_role author
dc.contributor.none.fl_str_mv Fernández Megía, Eduardo
Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)
dc.subject.none.fl_str_mv Boronic Acid
Dynamic Covalent Chemistry
Bioactive Polymeric Materials
230403 Polímeros compuestos
230408 Macromoléculas
topic Boronic Acid
Dynamic Covalent Chemistry
Bioactive Polymeric Materials
230403 Polímeros compuestos
230408 Macromoléculas
description The discovery of new structure-activity relationships represents a promising avenue for designing innovative materials and understanding the principles governing biological processes. Nevertheless, advances in this field have been limited by current methodologies used in the preparation of polymeric structures. In this context, dynamic covalent chemistry emerges as a valuable tool for developing highly adaptable materials. This thesis aims to bridge these two concepts. By employing a dendrimer and a dendritic block copolymer as bricks, and the fast-forming and strong boronate bond as cement, a novel technology has been developed for constructing bioactive materials with implications in drug delivery, gene therapy, and the fabrication of artificial cells.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-01-01
2024
2024-01-01
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv https://hdl.handle.net/10347/37798
url https://hdl.handle.net/10347/37798
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
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