Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study

Intravenous zanamivir is a neuraminidase inhibitor suitable for treatment of hospitalized patients with severe influenza. Patients were treated with intravenous zanamivir 600 mg twice daily, adjusted for renal impairment, for up to 10 days. Primary outcomes included adverse events (AEs), and clinica...

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Detalhes bibliográficos
Autores: Marty, F. M., Man, C. Y., Van der Horst, C., Francois, B., Garot, D., Mánez, R., Thamlikitkul, V., Lorente Balanza, José Ángel, Álvarez Lerma, Francisco, Brealey, D., Zhao, H. H., Weller, S., Yates, P. J., Peppercorn, A. F.
Formato: artículo
Fecha de publicación:2014
País:España
Recursos:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:español
OAI Identifier:oai:abacus.universidadeuropea.com:11268/4210
Acesso em linha:http://hdl.handle.net/11268/4210
Access Level:acceso abierto
Palavra-chave:Zanamivir
Medicamentos
Investigación médica
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spelling Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II studyMarty, F. M.Man, C. Y.Van der Horst, C.Francois, B.Garot, D.Mánez, R.Thamlikitkul, V.Lorente Balanza, José ÁngelÁlvarez Lerma, FranciscoBrealey, D.Zhao, H. H.Weller, S.Yates, P. J.Peppercorn, A. F.ZanamivirMedicamentosInvestigación médicaIntravenous zanamivir is a neuraminidase inhibitor suitable for treatment of hospitalized patients with severe influenza. Patients were treated with intravenous zanamivir 600 mg twice daily, adjusted for renal impairment, for up to 10 days. Primary outcomes included adverse events (AEs), and clinical/laboratory parameters. Pharmacokinetics, viral load, and disease course were also assessed.20152015-07-1720142014-01-0120142014-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/11268/4210reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Españolspaopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/42102026-06-11T12:41:27Z
dc.title.none.fl_str_mv Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
title Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
spellingShingle Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
Marty, F. M.
Zanamivir
Medicamentos
Investigación médica
title_short Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
title_full Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
title_fullStr Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
title_full_unstemmed Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
title_sort Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study
dc.creator.none.fl_str_mv Marty, F. M.
Man, C. Y.
Van der Horst, C.
Francois, B.
Garot, D.
Mánez, R.
Thamlikitkul, V.
Lorente Balanza, José Ángel
Álvarez Lerma, Francisco
Brealey, D.
Zhao, H. H.
Weller, S.
Yates, P. J.
Peppercorn, A. F.
author Marty, F. M.
author_facet Marty, F. M.
Man, C. Y.
Van der Horst, C.
Francois, B.
Garot, D.
Mánez, R.
Thamlikitkul, V.
Lorente Balanza, José Ángel
Álvarez Lerma, Francisco
Brealey, D.
Zhao, H. H.
Weller, S.
Yates, P. J.
Peppercorn, A. F.
author_role author
author2 Man, C. Y.
Van der Horst, C.
Francois, B.
Garot, D.
Mánez, R.
Thamlikitkul, V.
Lorente Balanza, José Ángel
Álvarez Lerma, Francisco
Brealey, D.
Zhao, H. H.
Weller, S.
Yates, P. J.
Peppercorn, A. F.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Zanamivir
Medicamentos
Investigación médica
topic Zanamivir
Medicamentos
Investigación médica
description Intravenous zanamivir is a neuraminidase inhibitor suitable for treatment of hospitalized patients with severe influenza. Patients were treated with intravenous zanamivir 600 mg twice daily, adjusted for renal impairment, for up to 10 days. Primary outcomes included adverse events (AEs), and clinical/laboratory parameters. Pharmacokinetics, viral load, and disease course were also assessed.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01
2014
2014-01-01
2015
2015-07-17
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/4210
url http://hdl.handle.net/11268/4210
dc.language.none.fl_str_mv Español
spa
language_invalid_str_mv Español
language spa
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301629

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