Considering the Effects and Maternofoetal Implications of Vascular Disorders and the Umbilical Cord

The umbilical cord is a critical anatomical structure connecting the placenta with the foetus, fulfilling multiple functions during pregnancy and hence influencing foetal development, programming and survival. Histologically, the umbilical cord is composed of three blood vessels: two arteries and on...

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Detalles Bibliográficos
Autores: Sanchez Trujillo, Lara, García Montero, Cielo, Fraile Martínez, Oscar, Guijarro, Luis G., Bravo Arribas, Coral, León Luis, Juan Antonio, Saez, Jose V., Bujan, Julia, Álvarez Mon, Melchor, García Honduvilla, Natalio, Saez, Miguel A., Ortega, Miguel A.
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/72320
Acceso en línea:https://hdl.handle.net/20.500.14352/72320
Access Level:acceso abierto
Palabra clave:618.2 : 611.1
Umbilical cord
Vascular malperfusion
Pre-eclampsia
Chronic venous disease
Medicina
Ginecología y obstetricia
Sistema cardiovascular
32 Ciencias Médicas
3201.08 Ginecología
2411.03 Fisiología Cardiovascular
Descripción
Sumario:The umbilical cord is a critical anatomical structure connecting the placenta with the foetus, fulfilling multiple functions during pregnancy and hence influencing foetal development, programming and survival. Histologically, the umbilical cord is composed of three blood vessels: two arteries and one vein, integrated in a mucous connective tissue (Wharton’s jelly) upholstered by a layer of amniotic coating. Vascular alterations in the umbilical cord or damage in this tissue because of other vascular disorders during pregnancy are worryingly related with detrimental maternofoetal consequences. In the present work, we will describe the main vascular alterations presented in the umbilical cord, both in the arteries (Single umbilical artery, hypoplastic umbilical artery or aneurysms in umbilical arteries) and the vein (Vascular thrombosis, aneurysms or varicose veins in the umbilical vein), together with other possible complications (Velamentous insertion, vasa praevia, hypercoiled or hypocoiled cord, angiomyxoma and haematomas). Likewise, the effect of the main obstetric vascular disorders like hypertensive disorders of pregnancy (specially pre-eclampsia) and chronic venous disease on the umbilical cord will also be summarized herein.