A journey across dopamine Metabolism: A rotational study of DOPAC

Producción Científica

Detalhes bibliográficos
Autores: Sanz Novo, Miguel, Kolesniková, Lucie, Insausti, Aran, Alonso Hernández, José Luis, León Ona, Iker, Alonso Alonso, Elena Rita
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/58486
Acesso em linha:https://doi.org/10.1016/j.saa.2022.122303
https://uvadoc.uva.es/handle/10324/58486
Access Level:acceso abierto
Palavra-chave:Neurotransmitters
Epectroscopy
Neurotrasnsmisores
Espectroscopia de alta resolución
Espectroscopia rotacional
2206.07 Espectroscopia Molecular
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spelling A journey across dopamine Metabolism: A rotational study of DOPACSanz Novo, MiguelKolesniková, LucieInsausti, AranAlonso Hernández, José LuisLeón Ona, IkerAlonso Alonso, Elena RitaNeurotransmittersEpectroscopyNeurotrasnsmisoresEspectroscopia de alta resoluciónEspectroscopia rotacional2206.07 Espectroscopia MolecularProducción CientíficaDOPAC, a relevant scaffold in dopamine metabolism, was probed in the gas phase and interrogated by high-resolution rotational spectroscopy. Herein, three distinct conformers were isolated in a supersonic jet and identified for the first time through an examination of the trend of the rotational constants and the dipole moment selection rules. Additionally, we examined the plausible relaxation pathways of the low-energy conformers of DOPAC, which helped us to claim the indirect detection of two additional conformers, providing conclusive experimental evidence of the flexible nature of this biomolecule. The current investigation sheds some light on the differences between jet-cooled rotational experiments and matrix-isolation infrared spectroscopy.Ministerio de Ciencia e Innovación (CTQ2016-76393-P and PID2019- 111396 GB-I00)Junta de Castilla y León (VA077U16 and VA244P20)European Research Council under the European Union’s Seventh Framework Programme (FP/2007- 2013)/ERC-2013-SyG, Grant Agreement n. 610256 NANOCOSMOSElsevier2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.1016/j.saa.2022.122303https://uvadoc.uva.es/handle/10324/58486reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.sciencedirect.com/science/article/pii/S1386142522014512?via%3Dihubinfo:eu-repo/grantAgreement/EC/H2020/610256info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:uvadoc.uva.es:10324/584862026-06-13T12:44:47Z
dc.title.none.fl_str_mv A journey across dopamine Metabolism: A rotational study of DOPAC
title A journey across dopamine Metabolism: A rotational study of DOPAC
spellingShingle A journey across dopamine Metabolism: A rotational study of DOPAC
Sanz Novo, Miguel
Neurotransmitters
Epectroscopy
Neurotrasnsmisores
Espectroscopia de alta resolución
Espectroscopia rotacional
2206.07 Espectroscopia Molecular
title_short A journey across dopamine Metabolism: A rotational study of DOPAC
title_full A journey across dopamine Metabolism: A rotational study of DOPAC
title_fullStr A journey across dopamine Metabolism: A rotational study of DOPAC
title_full_unstemmed A journey across dopamine Metabolism: A rotational study of DOPAC
title_sort A journey across dopamine Metabolism: A rotational study of DOPAC
dc.creator.none.fl_str_mv Sanz Novo, Miguel
Kolesniková, Lucie
Insausti, Aran
Alonso Hernández, José Luis
León Ona, Iker
Alonso Alonso, Elena Rita
author Sanz Novo, Miguel
author_facet Sanz Novo, Miguel
Kolesniková, Lucie
Insausti, Aran
Alonso Hernández, José Luis
León Ona, Iker
Alonso Alonso, Elena Rita
author_role author
author2 Kolesniková, Lucie
Insausti, Aran
Alonso Hernández, José Luis
León Ona, Iker
Alonso Alonso, Elena Rita
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Neurotransmitters
Epectroscopy
Neurotrasnsmisores
Espectroscopia de alta resolución
Espectroscopia rotacional
2206.07 Espectroscopia Molecular
topic Neurotransmitters
Epectroscopy
Neurotrasnsmisores
Espectroscopia de alta resolución
Espectroscopia rotacional
2206.07 Espectroscopia Molecular
description Producción Científica
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1016/j.saa.2022.122303
https://uvadoc.uva.es/handle/10324/58486
url https://doi.org/10.1016/j.saa.2022.122303
https://uvadoc.uva.es/handle/10324/58486
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S1386142522014512?via%3Dihub
info:eu-repo/grantAgreement/EC/H2020/610256
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,198674

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