SEOM clinical guideline for treatment of kidney cancer (2017)

The goal of this article is to provide recommendations about the management of kidney cancer. Based on pathologic and molecular features, several kidney cancer variants were described. Nephron-sparing techniques are the gold standard of localized disease. After a randomized trial, sunitinib could be...

Descripción completa

Detalles Bibliográficos
Autores: Gallardo, Enrique, Méndez-Vidal, María José, Perez-Gracia, Jose Luis, Sepúlveda-Sánchez, Juan Manuel, Campayo Guillaumes, Marc, Chirivella González, Isabel, García del Muro Solans, Xavier, González del Alba, Aránzazu, Grande, Enrique, Suarez, Cristina
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/171994
Acceso en línea:https://hdl.handle.net/2445/171994
Access Level:acceso abierto
Palabra clave:Càncer
Ronyó
Tractament adjuvant del càncer
Cancer
Kidney
Adjuvant treatment of cancer
Descripción
Sumario:The goal of this article is to provide recommendations about the management of kidney cancer. Based on pathologic and molecular features, several kidney cancer variants were described. Nephron-sparing techniques are the gold standard of localized disease. After a randomized trial, sunitinib could be considered in adjuvant treatment in high-risk patients. Patients with advanced disease constitute a heterogeneous population. Prognostic classification should be considered. Both sunitinib and pazopanib are the standard options for first-line systemic therapy in advanced renal cell carcinoma. Based on the results of two randomized trials, both nivolumab and cabozantinib should be considered the standard for second and further lines of therapy. Response evaluation for present therapies is a challenge.