Predictors of hypertension remission and recurrence after bariatric surgery

BACKGROUND: Few data exist on factors associated with hypertension (HTN) remission post-bariatric surgery. No information on factors that may predict HTN relapse is available. The aims were to assess the HTN remission and relapse rates at 1 and 3 years, respectively, post-bariatric surgery, and dete...

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Detalles Bibliográficos
Autores: Benaiges Foix, David, Sagué Vilavella, Maria, Flores Le Roux, Juana Antonia, Pedro-Botet, Juan, Ramón Moros, José Manuel, Villatoro Moreno, Montserrat, Chillarón Jordan, Juan José, Pera Román, Manuel, Más-Lorenzo, Antonio, Grande Posa, Luís, Goday Arnó, Albert
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2016
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/26238
Acceso en línea:http://hdl.handle.net/10230/26238
http://dx.doi.org/10.1093/ajh/hpv153
Access Level:acceso abierto
Palabra clave:Obesitat -- Cirurgia
Pressió sanguínia
Hipertensió
Descripción
Sumario:BACKGROUND: Few data exist on factors associated with hypertension (HTN) remission post-bariatric surgery. No information on factors that may predict HTN relapse is available. The aims were to assess the HTN remission and relapse rates at 1 and 3 years, respectively, post-bariatric surgery, and determine predictive factors. METHODS: A nonrandomized prospective cohort study on severely obese patients undergoing laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) with a follow-up of 36 months was conducted between 2005 and 2011. Criteria for HTN diagnosis were current treatment with antihypertensive agents and/or systolic blood pressure (BP) >140mm Hg and/or diastolic BP >90mm Hg. HTN remission was defined as normalization of BP maintained after discontinuation of medical treatment. RESULTS: A total of 197 patients were included in the study. HTN was present in 47.7%; 68.1% of hypertensive patients showed HTN remission 1 year after the surgical procedure, 21.9% of whom had relapsed at 3 years. The number of antihypertensive drugs prior to surgery was associated with a lower remission rate at the first year and a higher recurrence at 3 years. However, a smaller weight loss during the first year was associated with increased HTN recurrence at 3 years. CONCLUSION: HTN relapses in 1 of 5 hypertensives who have achieved remission at the first year of follow-up. Weight loss during the first postoperative year should be encouraged to avoid HTN relapse at 3 years.