Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study

Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-mat...

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Detalles Bibliográficos
Autores: Papantoniou K, Castaño-Vinyals G, Espinosa A, Turner MC, Martín-Sánchez V, Casabonne D, Aragonés N, Gómez-Acebo I, Ardanaz E, Jimenez-Moleon JJ, Amiano P, Molina-Barceló A, Alguacil J, Fernández-Tardón G, Huerta JM, Hernández-Segura N, Perez-Gomez B, Llorca J, Vidán-Alli J, Olmedo-Requena R, Gil L, Castañon-López C, Pollan M, Kogevinas M, Moreno V
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p9939
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/9939
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107177458&doi=10.1038%2fs41598-021-91275-3&partnerID=40&md5=c5cddf98bfaba3a06589fe950e2d4b87
Access Level:acceso abierto
Palabra clave:Aged
Body Mass Index
Case-Control Studies
Colorectal Neoplasms
Female
Humans
Male
Middle Aged
Multivariate Analysis
Sleep
Spain
Stomach Neoplasms
aged
body mass
case control study
colorectal tumor
female
human
male
middle aged
multivariate analysis
pathophysiology
physiology
sleep
stomach tumor
Descripción
Sumario:Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case-control study (2008-2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (<= 5, 6, 7, 8,>= 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal (OR >= 9 hours: 1.59; 95%CI 1.30-1.94) and gastric cancer (OR >= 9 hours: 1.95; 1.37-2.76); short sleep was associated with increased odds of gastric cancer (OR <= 5 hours: 1.32; 0.93-1.88). Frequent and long daytime naps increased the odds of colorectal (OR6-7 naps/week, >= 30 min: 1.32; 1.14-1.54) and gastric cancer (OR6-7 naps/week, >= 30 min: 1.56; 1.21-2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.

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