Tryptophan depletion affects compulsive behaviour in rats: strain dependent effects and associated neuromechanisms

[Rationale] Compulsive behaviour, present in different psychiatric disorders, such as obsessive-compulsive disorder, schizophrenia and drug abuse, is associated with altered levels of monoamines, particularly serotonin (5-hydroxytryptamine) and its receptor system.

Detalles Bibliográficos
Autores: Merchán, Ana, Navarro, S. V., Klein, Anders Bue, Aznar, Susana, Campa, Leticia, Suñol, Cristina, Moreno, Margarita, Flores, Pilar
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/177194
Acceso en línea:http://hdl.handle.net/10261/177194
Access Level:acceso abierto
Palabra clave:Compulsivity
Inhibitory control
Chronic tryptophan depletion
Schedule-induced polydipsia
Monoamines
5-HT2A binding
Descripción
Sumario:[Rationale] Compulsive behaviour, present in different psychiatric disorders, such as obsessive-compulsive disorder, schizophrenia and drug abuse, is associated with altered levels of monoamines, particularly serotonin (5-hydroxytryptamine) and its receptor system.