Inaccurate cortical tracking of speech in adults with impaired speech perception in noise

Published:10 September 2021

Detalles Bibliográficos
Autores: Vander Ghinst, Marc, Bourguignon, Mathieu, Wens, Vincent, Naeije, Gilles, Ducène, Cecile, Niesen, Maxime, Hassid, Sergio, Choufani, Georges, Goldman, Serge, De Tiège, Xavier
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/55171
Acceso en línea:http://hdl.handle.net/10810/55171
Access Level:acceso abierto
Palabra clave:magnetoencephalography
coherence analysis
functional connectivity
speech-in-noise
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oai_identifier_str oai:addi.ehu.eus:10810/55171
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
title Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
spellingShingle Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
Vander Ghinst, Marc
magnetoencephalography
coherence analysis
functional connectivity
speech-in-noise
title_short Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
title_full Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
title_fullStr Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
title_full_unstemmed Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
title_sort Inaccurate cortical tracking of speech in adults with impaired speech perception in noise
dc.creator.none.fl_str_mv Vander Ghinst, Marc
Bourguignon, Mathieu
Wens, Vincent
Naeije, Gilles
Ducène, Cecile
Niesen, Maxime
Hassid, Sergio
Choufani, Georges
Goldman, Serge
De Tiège, Xavier
author Vander Ghinst, Marc
author_facet Vander Ghinst, Marc
Bourguignon, Mathieu
Wens, Vincent
Naeije, Gilles
Ducène, Cecile
Niesen, Maxime
Hassid, Sergio
Choufani, Georges
Goldman, Serge
De Tiège, Xavier
author_role author
author2 Bourguignon, Mathieu
Wens, Vincent
Naeije, Gilles
Ducène, Cecile
Niesen, Maxime
Hassid, Sergio
Choufani, Georges
Goldman, Serge
De Tiège, Xavier
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv magnetoencephalography
coherence analysis
functional connectivity
speech-in-noise
topic magnetoencephalography
coherence analysis
functional connectivity
speech-in-noise
description Published:10 September 2021
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/55171
url http://hdl.handle.net/10810/55171
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/MINECO/PSI2016-77175-P/
info:eu-repo/grantAgreement/EC/H2020/MC
https://academic.oup.com/braincomms
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Brain Communications
publisher.none.fl_str_mv Brain Communications
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869403244448448512
spelling Inaccurate cortical tracking of speech in adults with impaired speech perception in noiseVander Ghinst, MarcBourguignon, MathieuWens, VincentNaeije, GillesDucène, CecileNiesen, MaximeHassid, SergioChoufani, GeorgesGoldman, SergeDe Tiège, Xaviermagnetoencephalographycoherence analysisfunctional connectivityspeech-in-noisePublished:10 September 2021Impaired speech perception in noise despite normal peripheral auditory function is a common problem in young adults. Despite a growing body of research, the pathophysiology of this impairment remains unknown. This magnetoencephalography study characterizes the cortical tracking of speech in a multi-talker background in a group of highly selected adult subjects with impaired speech perception in noise without peripheral auditory dysfunction. Magnetoencephalographic signals were recorded from 13 subjects with impaired speech perception in noise (six females, mean age: 30 years) and matched healthy subjects while they were listening to 5 different recordings of stories merged with a multi-talker background at different signal to noise ratios (No Noise, þ10, þ5, 0 and 5dB). The cortical tracking of speech was quantified with coherence between magnetoencephalographic signals and the temporal envelope of (i) the global auditory scene (i.e. the attended speech stream and the multi-talker background noise), (ii) the attended speech stream only and (iii) the multi-talker background noise. Functional connectivity was then estimated between brain areas showing altered cortical tracking of speech in noise in subjects with impaired speech perception in noise and the rest of the brain. All participants demonstrated a selective cortical representation of the attended speech stream in noisy conditions, but subjects with impaired speech perception in noise displayed reduced cortical tracking of speech at the syllable rate (i.e. 4–8Hz) in all noisy conditions. Increased functional connectivity was observed in subjects with impaired speech perception in noise in Noiseless and speech in noise conditions between supratemporal auditory cortices and left-dominant brain areas involved in semantic and attention processes. The difficulty to understand speech in a multi-talker background in subjects with impaired speech perception in noise appears to be related to an inaccurate auditory cortex tracking of speech at the syllable rate. The increased functional connectivity between supratemporal auditory cortices and language/attention-related neocortical areas probably aims at supporting speech perception and subsequent recognition in adverse auditory scenes. Overall, this study argues for a central origin of impaired speech perception in noise in the absence of any peripheral auditory dysfunction.Marc Vander Ghinst, Gilles Naeije and Maxime Niesen were supported by a research grant from the Fonds Erasme (Brussels, Belgium). Mathieu Bourguignon was supported by the Program Attract of Innoviris (grant 2015-BB2B-10), Spanish Ministry of Economy and Competitiveness (grant PSI2016-77175-P) and Marie Skłodowska-Curie Action of the European Commission (grant 743562). Gilles Naeije and Xavier De Tie`ge are Post-doctorate Clinical Master Specialist at the Fonds de la Recherche Scientifique (FRS-FNRS, Brussels, Belgium). This study and the MEG project at the CUB Hoˆpital Erasme were financially supported by the Fonds Erasme (Research Convention ‘Les Voies du Savoir’, Fonds Erasme, Brussels, Belgium).Brain Communications202220222021info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/55171reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoInglésinfo:eu-repo/grantAgreement/MINECO/PSI2016-77175-P/info:eu-repo/grantAgreement/EC/H2020/MChttps://academic.oup.com/braincommsinfo:eu-repo/semantics/openAccessVC The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.oai:addi.ehu.eus:10810/551712026-06-18T09:23:17Z
score 15,301603

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