Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis

Despite the rapid increase in evidence from the past decade on daily steps and health-related outcomes, existing systematic reviews primarily focused on few outcomes, such as all-cause mortality. This study synthesised the prospective dose-response relationship between daily steps and health outcome...

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Detalles Bibliográficos
Autores: Ding, Ding, Nguyen, Binh, Nau, Tracy, Luo, Mengyun, Pozo Cruz, Borja del, Dempsey, Paddy, Munn, Zachary, Jefferis, Barbara, Sherrington, Cathie, Calleja, Elizabeth, Et. al.
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/16717
Acceso en línea:https://hdl.handle.net/11268/16717
Access Level:acceso abierto
Palabra clave:Relación dosis-respuesta inmunológica
Revisión sistemática
Metaanálisis
Medicina preventiva
Investigación médica
Educación sanitaria
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Descripción
Sumario:Despite the rapid increase in evidence from the past decade on daily steps and health-related outcomes, existing systematic reviews primarily focused on few outcomes, such as all-cause mortality. This study synthesised the prospective dose-response relationship between daily steps and health outcomes including all-cause mortality, cardiovascular disease, cancer, type 2 diabetes, cognitive outcomes, mental health outcomes, physical function, and falls. This systematic review and meta-analysis searched through PubMed and EBSCO CINAHL for literature published between Jan 1, 2014, and Feb 14, 2025, supplemented by other search strategies. Eligible prospective studies examined the relationship between device-measured daily steps and health outcomes among adults without restrictions on language or publication type. Pairs of reviewers (BN, KO, ML, and TN) independently did the study selection, data extraction, and risk of bias assessment using the 9-point Newcastle-Ottawa Scale. Hazard ratios (HRs) from individual studies were synthesised using random-effects dose-response meta-analysis where possible. Certainty of evidence was assessed using GRADE. This trial is registered with PROSPERO (CRD42024529706).

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