Crimean-Congo haemorrhagic fever (CCHF) virus-specific antibody detection in blood donors, Castile-León, Spain, summer 2017 and 2018.

[EN] BackgroundCrimean-Congo haemorrhagic fever virus (CCHFV) is considered an emerging or even a probable re-emerging pathogen in southern Europe. Presence of this virus had been reported previously in Spain in 2010.AimWe aimed to evaluate the potential circulation of CCHFV in western Spain with a...

ver descrição completa

Detalhes bibliográficos
Autores: Monsalve Arteaga, Lía Carolina, Muñoz Bellido, Juan Luis, Vieira Lista, María Carmen, Vicente Santiago, María Belén, Fernández Soto, Pedro, Bas, Isabel, Leralta, Nuria, Ory Manchón, Fernando de, Negredo, Ana Isabel, Sánchez Seco, María Paz, Alonso Sardón, Montserrat, Pérez González, Sonia, Jiménez Del Bianco, Ana, Blanco Peris, Lydia, Álamo Sanz, Rufino, Hewson, Roger, Belhassen García, Moncef, Muro Álvarez, Antonio
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/163268
Acesso em linha:http://hdl.handle.net/10366/163268
Access Level:acceso abierto
Palavra-chave:Blood Donors Hemorrhagic Fever Virus
Crimean-Congo Hemorrhagic Fever
Crimean Seroepidemiologic Studies Spain Ticks
Ticks
Seroepidemiologic Studies
Blood Donors
3207.12 Parasitología
garrapatas
donantes de sangre
estudios seroepidemiológicos
Descrição
Resumo:[EN] BackgroundCrimean-Congo haemorrhagic fever virus (CCHFV) is considered an emerging or even a probable re-emerging pathogen in southern Europe. Presence of this virus had been reported previously in Spain in 2010.AimWe aimed to evaluate the potential circulation of CCHFV in western Spain with a serosurvey in asymptomatic adults (blood donors).MethodsDuring 2017 and 2018, we conducted a CCHFV serosurvey in randomly selected asymptomatic blood donors from western Spain. Three assays using specific IgG antibodies against CCHFV were performed: the VectoCrimea ELISA test, an in-house ELISA and indirect immunofluorescence (EuroImmun) test with glycoprotein and nucleoprotein.ResultsA total of 516 blood donors participated in this cross-sectional study. The majority of the study participants were male (68.4%), and the mean age was 46.3 years. Most of the participants came from rural areas (86.8%) and 68.6% had contact with animals and 20.9% had animal husbandry practices. One in five participants (109/516, 21.1%) were engaged in at-risk professional activities such as agriculture and shepherding, slaughtering, hunting, veterinary and healthcare work (mainly nursing staff and laboratory technicians). A total of 15.3% of the participants were bitten by ticks in the days or months before the date of sampling. We detected anti-CCHFV IgG antibodies with two diagnostic assays in three of the 516 individuals and with one diagnostic assay in six of the 516 individuals.ConclusionSeroprevalence of CCHFV was between 0.58% and 1.16% in Castile-León, Spain. This is the first study in western Spain that showed circulation of CCHFV in healthy people.

Registos relacionados