The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.

BACKGROUND: Low handgrip strength has been shown to be associated with higher levels of depressive symptoms. One area of mental health that is understudied in relation to grip strength is chronic stress, which can exist independently to depression, or as a comorbidity or precursor to this condition....

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Autores: Smith L, Firth J, Grabovac I, Koyanagi A, Veronese N, Stubbs B, Soysal P, Yang L, Jackson SE
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p16352
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16352
Access Level:acceso abierto
Palabra clave:depression
depressive symptoms
grip strength
hair cortisol
older adults
physical function
stress
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spelling The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.Smith LFirth JGrabovac IKoyanagi AVeronese NStubbs BSoysal PYang LJackson SEdepressiondepressive symptomsgrip strengthhair cortisololder adultsphysical functionstressBACKGROUND: Low handgrip strength has been shown to be associated with higher levels of depressive symptoms. One area of mental health that is understudied in relation to grip strength is chronic stress, which can exist independently to depression, or as a comorbidity or precursor to this condition. The present study examined cross-sectional associations between grip strength, an established marker of physical function, and (a) depressive symptoms and (b) chronic stress utilizing hair cortisol concentrations, while accounting for multiple pertinent confounding variables. METHOD: Data were used from wave 6 (2012/13) of the English Longitudinal Study of Aging, a panel study of older (=50 years) community-dwelling men and women. Grip strength was measured in kg using a hand-held dynamometer. Depressive symptoms were assessed using the 8-item Center for Epidemiologic Studies Depression scale. Hair cortisol concentrations (pg/mg) were determined from samples of scalp hair and log-transformed for analysis to correct skewness. Associations of grip strength with depressive symptoms and hair cortisol concentration were tested using linear regression models adjusted for age, sex, ethnicity, wealth, smoking status, physical activity, body mass index, limiting long-standing illness, arthritis, diabetes, and hair treatment. RESULTS: The sample comprised of 3741 participants (mean age 68.4 years, 66.4% female). After adjustment for age and sex, grip strength was significantly and negatively associated with both depressive symptoms (B = -0.038, SE = 0.004, P < 0.001) and hair cortisol (B = -0.003, SE = 0.001, P = 0.029). However, in the fully-adjusted models, both associations were attenuated and only the association with depressive symptoms remained statistically significant (B = -0.015, SE = 0.004, P < 0.001; hair cortisol B = -0.002, SE = 0.001, P = 0.088). CONCLUSION: In a large sample of older adults in England, grip strength was negatively associated with depressive symptoms. Results were inconclusive regarding the association between grip strength and chronic stress. Further research examining the longitudinal relationships between muscular strength and specific aspects of mental health, while also exploring the neurobiological mechanisms underlying these associations, is warranted before recommendations for policy and practice can be made.WILEY2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16352SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTSISSN: 09057188ISSNe: 16000838reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p163522026-05-27T12:37:41Z
dc.title.none.fl_str_mv The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
title The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
spellingShingle The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
Smith L
depression
depressive symptoms
grip strength
hair cortisol
older adults
physical function
stress
title_short The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
title_full The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
title_fullStr The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
title_full_unstemmed The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
title_sort The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
dc.creator.none.fl_str_mv Smith L
Firth J
Grabovac I
Koyanagi A
Veronese N
Stubbs B
Soysal P
Yang L
Jackson SE
author Smith L
author_facet Smith L
Firth J
Grabovac I
Koyanagi A
Veronese N
Stubbs B
Soysal P
Yang L
Jackson SE
author_role author
author2 Firth J
Grabovac I
Koyanagi A
Veronese N
Stubbs B
Soysal P
Yang L
Jackson SE
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv depression
depressive symptoms
grip strength
hair cortisol
older adults
physical function
stress
topic depression
depressive symptoms
grip strength
hair cortisol
older adults
physical function
stress
description BACKGROUND: Low handgrip strength has been shown to be associated with higher levels of depressive symptoms. One area of mental health that is understudied in relation to grip strength is chronic stress, which can exist independently to depression, or as a comorbidity or precursor to this condition. The present study examined cross-sectional associations between grip strength, an established marker of physical function, and (a) depressive symptoms and (b) chronic stress utilizing hair cortisol concentrations, while accounting for multiple pertinent confounding variables. METHOD: Data were used from wave 6 (2012/13) of the English Longitudinal Study of Aging, a panel study of older (=50 years) community-dwelling men and women. Grip strength was measured in kg using a hand-held dynamometer. Depressive symptoms were assessed using the 8-item Center for Epidemiologic Studies Depression scale. Hair cortisol concentrations (pg/mg) were determined from samples of scalp hair and log-transformed for analysis to correct skewness. Associations of grip strength with depressive symptoms and hair cortisol concentration were tested using linear regression models adjusted for age, sex, ethnicity, wealth, smoking status, physical activity, body mass index, limiting long-standing illness, arthritis, diabetes, and hair treatment. RESULTS: The sample comprised of 3741 participants (mean age 68.4 years, 66.4% female). After adjustment for age and sex, grip strength was significantly and negatively associated with both depressive symptoms (B = -0.038, SE = 0.004, P < 0.001) and hair cortisol (B = -0.003, SE = 0.001, P = 0.029). However, in the fully-adjusted models, both associations were attenuated and only the association with depressive symptoms remained statistically significant (B = -0.015, SE = 0.004, P < 0.001; hair cortisol B = -0.002, SE = 0.001, P = 0.088). CONCLUSION: In a large sample of older adults in England, grip strength was negatively associated with depressive symptoms. Results were inconclusive regarding the association between grip strength and chronic stress. Further research examining the longitudinal relationships between muscular strength and specific aspects of mental health, while also exploring the neurobiological mechanisms underlying these associations, is warranted before recommendations for policy and practice can be made.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16352
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16352
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv WILEY
publisher.none.fl_str_mv WILEY
dc.source.none.fl_str_mv SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
ISSN: 09057188
ISSNe: 16000838
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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