3D Genome Architecture

The tridimensional (3D) organization of the genome is just beginning to be understood and, despite the tremendous progress witnessed in the recent years, many essential questions remain unanswered. Major methodological and conceptual challenges need to be overcome to reach a comprehensive view of th...

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Detalles Bibliográficos
Autores: Azorín, Ferran, Jordan, Albert, Maeso, Ignacio, Manzanares, Miguel, Rada-Iglesias, Álvaro, Roca, Joaquim, Rotllant, Josep, Vicent, Guillermo P.
Tipo de recurso: otro
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/250696
Acceso en línea:http://hdl.handle.net/10261/250696
Access Level:acceso abierto
Palabra clave:3D
Genome architecture
TAD
Compartment
3C
Imaging
Descripción
Sumario:The tridimensional (3D) organization of the genome is just beginning to be understood and, despite the tremendous progress witnessed in the recent years, many essential questions remain unanswered. Major methodological and conceptual challenges need to be overcome to reach a comprehensive view of the physiological impact of 3D genome architecture in health and disease. CSIC is in a privileged position to undertake these challenges