Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain

Background In recent years, Aichi virus (AiV) has been involved in acute viral gastroenteritis outbreaks. However, the common pathogenesis of AiV releases more in subclinical infections underestimating the impact of AiV in human health. Objectives The present study describes the presence and genetic...

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Autores: Rivadulla Veira, Enrique, Varela, Miguel F., López Romalde, Jesús
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/38864
Acceso en línea:https://hdl.handle.net/10347/38864
Access Level:acceso abierto
Palabra clave:Aichi virus
Genotyping
Epidemiology
Gastroenteritis
2420 Virología
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spelling Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern SpainRivadulla Veira, EnriqueVarela, Miguel F.López Romalde, JesúsAichi virusGenotypingEpidemiologyGastroenteritis2420 VirologíaBackground In recent years, Aichi virus (AiV) has been involved in acute viral gastroenteritis outbreaks. However, the common pathogenesis of AiV releases more in subclinical infections underestimating the impact of AiV in human health. Objectives The present study describes the presence and genetic diversity of AiV in patients with gastroenteritis in Northwestern Spain. Study design: A total of 2667 stool samples, obtained between July 2010 and June 2011, from diarrheic outpatients were studied for detection and molecular characterization of AiV using PCR techniques followed by sequencing and phylogenetic analyses. Results The virus was detected in 124 (5.0%) of the samples among all age groups. Coinfections were also detected, from the 124 positive samples, 72 (58.1%) were positive only for AiV, whereas mixed contaminations with Norovirus genogroup I or genogroup II, Sapovirus, or other enteric pathogens were detected in 52 (41.9%) samples. A total of 70 positive samples could be genotyped, being characterized as genotype A (58.6%) or B (41.4%). AiV was detected from August to April, being the highest number of AiV positive samples detected during autumn and winter seasons. Conclusions This survey remarks the importance of emerging enteric viruses in patients who require medical assistance, and offers more information about the real importance of AiV as gastroenteritis agent.ElsevierUniversidade de Santiago de Compostela. Departamento de Microbioloxía e Parasitoloxía20192019-09-0120192019-09-01journal articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10347/38864reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/388642026-06-15T12:47:27Z
dc.title.none.fl_str_mv Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
title Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
spellingShingle Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
Rivadulla Veira, Enrique
Aichi virus
Genotyping
Epidemiology
Gastroenteritis
2420 Virología
title_short Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
title_full Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
title_fullStr Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
title_full_unstemmed Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
title_sort Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain
dc.creator.none.fl_str_mv Rivadulla Veira, Enrique
Varela, Miguel F.
López Romalde, Jesús
author Rivadulla Veira, Enrique
author_facet Rivadulla Veira, Enrique
Varela, Miguel F.
López Romalde, Jesús
author_role author
author2 Varela, Miguel F.
López Romalde, Jesús
author2_role author
author
dc.contributor.none.fl_str_mv Universidade de Santiago de Compostela. Departamento de Microbioloxía e Parasitoloxía
dc.subject.none.fl_str_mv Aichi virus
Genotyping
Epidemiology
Gastroenteritis
2420 Virología
topic Aichi virus
Genotyping
Epidemiology
Gastroenteritis
2420 Virología
description Background In recent years, Aichi virus (AiV) has been involved in acute viral gastroenteritis outbreaks. However, the common pathogenesis of AiV releases more in subclinical infections underestimating the impact of AiV in human health. Objectives The present study describes the presence and genetic diversity of AiV in patients with gastroenteritis in Northwestern Spain. Study design: A total of 2667 stool samples, obtained between July 2010 and June 2011, from diarrheic outpatients were studied for detection and molecular characterization of AiV using PCR techniques followed by sequencing and phylogenetic analyses. Results The virus was detected in 124 (5.0%) of the samples among all age groups. Coinfections were also detected, from the 124 positive samples, 72 (58.1%) were positive only for AiV, whereas mixed contaminations with Norovirus genogroup I or genogroup II, Sapovirus, or other enteric pathogens were detected in 52 (41.9%) samples. A total of 70 positive samples could be genotyped, being characterized as genotype A (58.6%) or B (41.4%). AiV was detected from August to April, being the highest number of AiV positive samples detected during autumn and winter seasons. Conclusions This survey remarks the importance of emerging enteric viruses in patients who require medical assistance, and offers more information about the real importance of AiV as gastroenteritis agent.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-09-01
2019
2019-09-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10347/38864
url https://hdl.handle.net/10347/38864
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
repository.mail.fl_str_mv
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