Click-tambjamines as efficient and tunable bioactive anion transporters

A novel class of transmembrane anion carriers, the click-tambjamines, display remarkable anionophoric activities in model liposomes and living cells. The versatility of this building block for the generation of molecular diversity offers promise to develop future drugs based on this design.

Detalles Bibliográficos
Autores: Carreira-Barral, Israel, Mielczarek, Marcin, Alonso-Carrillo, Daniel, Capurro, Valeria, Soto Cerrato, Vanessa, Pérez Tomás, Ricardo E., Caci, Emanuela, García Valverde, María, Quesada, Roberto
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/163058
Acceso en línea:https://hdl.handle.net/2445/163058
Access Level:acceso abierto
Palabra clave:Farmacologia
Pirroles
Anions
Pharmacology
Pyrroles
Descripción
Sumario:A novel class of transmembrane anion carriers, the click-tambjamines, display remarkable anionophoric activities in model liposomes and living cells. The versatility of this building block for the generation of molecular diversity offers promise to develop future drugs based on this design.

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