Low CD4/CD8 ratio is associated with increased morbidity and mortality in late and non-late presenters: results from a multicentre cohort study, 2004-2018

[Background] To study whether the association between the CD4/CD8 ratio variation over time and the development of clinical outcomes vary in late presenters (CD4 count < 350/µL or AIDS event at enrolment) or advanced presenters (CD4 count < 200/µL or AIDS event at enrolment).

Detalhes bibliográficos
Autores: Domínguez-Domínguez, Lourdes, Rava, Marta, Bisbal, Otilia, López-Cortés, Luis Eduardo, Portilla, Joaquín, Podzamczer, Daniel, Olalla, Julián, Fuster, Daniel, Rubio, Rafael, Jarrín, Inma, Iribarren, José A., Moreno, Santiago
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/306680
Acesso em linha:http://hdl.handle.net/10261/306680
https://api.elsevier.com/content/abstract/scopus_id/85128487359
Access Level:acceso abierto
Palavra-chave:AIDS events
CD4/CD8
Clinical outcomes
Late presentation
Mortality
Serious non-AIDS events
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
Descrição
Resumo:[Background] To study whether the association between the CD4/CD8 ratio variation over time and the development of clinical outcomes vary in late presenters (CD4 count < 350/µL or AIDS event at enrolment) or advanced presenters (CD4 count < 200/µL or AIDS event at enrolment).

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