Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic and astigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjects underwent a surgical procedur...

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Detalles Bibliográficos
Autores: Sánchez-González, José-María, Alonso-Aliste, Federico, Borroni, Davide, Amián-Cordero, Jonatan, De-Hita-Cantalejo, Concepción, Capote-Puente, Raúl, Bautista-Llamas, María-José, Sánchez González, María Carmen, Rodríguez-Calvo-de-Mora, Marina, Rocha-de-Lossada, Carlos
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/698166
Acceso en línea:http://hdl.handle.net/10486/698166
https://dx.doi.org/10.3390/jcm10091939
Access Level:acceso abierto
Palabra clave:plasma rich in growth factor
photorefractive keratectomy
transepithelial photorefractive keratectomy
visual outcomes
refractive outcomes
Medicina
Descripción
Sumario:To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic and astigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjects underwent a surgical procedure between February 2019 and June 2019. A three-month follow-up was recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelialization time recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visual acuity (UDVA) was 20/20.31 (0.00 + - 0.02 LogMAR). A total of 98% of eyes did not change corrected distance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was - 2.67 + 1.37 D and after three months changed to - 0.21 +- 0.34 D, and 2% of eyes changed 0.50 D or more between one and three months. Pain score was 3.29 +- 0.61 (3 to 6) score points at day one and 0.08 + 0.27 score points at day seven. Finally, re-epithelialization time was 2.50 +- 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems to alleviate immediate postoperative pain and positively contribute to corneal re-epithelization time