Role of the transcription factor NRF2 in maintaining the integrity of the Blood-Brain Barrier
[Background]: The Blood-Brain Barrier (BBB) is a complex and dynamic interface that regulates the exchange of molecules and cells between the blood and the central nervous system. It undergoes structural and functional throughout oxidative stress and inflammation, which may compromise its integrity...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/383844 |
| Acceso en línea: | http://hdl.handle.net/10261/383844 |
| Access Level: | acceso abierto |
| Palabra clave: | NRF2 Blood-Brain Barrier Inflammation Oxidative stress Neurological disorders Tight junction Phytochemicals |
| Sumario: | [Background]: The Blood-Brain Barrier (BBB) is a complex and dynamic interface that regulates the exchange of molecules and cells between the blood and the central nervous system. It undergoes structural and functional throughout oxidative stress and inflammation, which may compromise its integrity and contribute to the pathogenesis of neurodegenerative diseases. |
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