Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women

This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire...

Descripción completa

Detalles Bibliográficos
Autores: del Pozo, María del Pilar, Criado-Navarro, Inmaculada, Romieu, Isabelle, Chajès, Véronique, Priego-Capote, Feliciano, Pollan-Santamaria, Marina, Perez-Gomez, Beatriz, Sierra, Maria Angeles, de Lucas, Maria Pilar, Castelló Pastor, Adela, Ruiz Moreno, Emma, Fernandez de Larrea-Baz, Nerea, Pastor-Barriuso, Roberto, Lope Carvajal, Virginia
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/10879
Acceso en línea:http://hdl.handle.net/20.500.12105/10879
Access Level:acceso abierto
Palabra clave:Fatty acids
Obesity
Body mass index
Fat
Body Mass Index
Fats
Fatty Acids
Descripción
Sumario:This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography-mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids.

Similares en LA Referencia