Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort

Background: Uncertainty about the optimal respiratory support strategies in critically ill COVID-19 patients is wide‑ spread. While the risks and benefts of noninvasive techniques versus early invasive mechanical ventilation (IMV) are intensely debated, actual evidence is lacking. We sought to asses...

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Detalles Bibliográficos
Autores: Wendel Garcia, Pedro David, Aguirre Bermeo, Hernán, Buehler, Philipp K, Alfaro Farias, Mario, Yuen, Bernd, David, Sascha, Tschoellitsch, Thomas, Wengenmayer, Tobias, Korsos, Anita, Fogagnolo, Alberto, Kleger, Gian Reto, Wu, Madalena A, Colombo, Ricardo, Turrini, Fabrizio, Potalivo, Antonella, Rezoagli, Emanuele, Rodríguez García, Raquel, Castro Rebollo, Pedro, Lander Azcona, Arantxa, Martín Delgado, María Cruz, Lozano Gómez, Herminia, Ensner, Rolf, Michot, Marc P, Gehring, Nadine, Schott, Peter, Siegemund, Martin, Merki, Lukas, Wiegand, Jan, Jeitziner, Marie M, Laube, Marcus, Salomon, Petra, Hillgaertner, Frank, Dullenkopf, Alexander, Ksouri, Hatem, Cereghetti, Sara, Grazioli, Serge, Bürkle, Christian, Marrel, Julien, Fleisch, Isabelle, Perez, Marie-Helene
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/186729
Acceso en línea:https://hdl.handle.net/2445/186729
Access Level:acceso abierto
Palabra clave:COVID-19
Malalts en estat crític
Vellesa
Unitats de cures intensives
Critically ill
Old age
Intensive care units
Descripción
Sumario:Background: Uncertainty about the optimal respiratory support strategies in critically ill COVID-19 patients is wide‑ spread. While the risks and benefts of noninvasive techniques versus early invasive mechanical ventilation (IMV) are intensely debated, actual evidence is lacking. We sought to assess the risks and benefts of diferent respiratory sup‑ port strategies, employed in intensive care units during the frst months of the COVID-19 pandemic on intubation and intensive care unit (ICU) mortality rates. Methods: Subanalysis of a prospective, multinational registry of critically ill COVID-19 patients. Patients were subclas‑ sifed into standard oxygen therapy ≥10 L/min (SOT), high-fow oxygen therapy (HFNC), noninvasive positive-pressure

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