SEOM clinical guideline of diagnosis and management of low-grade glioma (2017)

Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definiti...

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Detalles Bibliográficos
Autores: Sepulveda-Sanchez, J. M., Munoz Langa, J., Arraez, M. A., Fuster, J., Hernandez-Lain, Aurelio, Reynes, Gaspar, Rodriguez Gonzalez, V., Vicente, Emilio, Vidal Denis, M., Gallego, Oscar
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/12105
Acceso en línea:https://hdl.handle.net/20.500.13003/12105
Access Level:acceso abierto
Palabra clave:Humans
Glioma
Brain Neoplasms
Humanos
Neoplasias Encefálicas
Astrocytoma
Oligodendroglioma
Low-grade glioma
Guideline
Neurooncology
Descripción
Sumario:Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk-benefit ratio of adjuvant treatment must be weighed for each individual.