Alkylation of oxazolones and related heterocycles through an SN1 reaction.

The alkylation of oxazolones through an SN1 reaction by using stabilized carbocations is reported. The reaction (catalyzed by Brønsted acids, such as TFA or thioureas) affords the final compounds in excellent yields. Reaction with other heterocycles has also been studied, rendering pyrazolone or oxi...

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Bibliographic Details
Authors: Alba, Andrea-Nekane R., Calvet Pallàs, Maria Teresa, Font Bardia, Ma. Mercedes, Moyano i Baldoire, Albert, Ríos Torres, Ramón
Format: article
Status:Versión enviada para evaluación y publicación
Publication Date:2011
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/34477
Online Access:https://hdl.handle.net/2445/34477
Access Level:Open access
Keyword:Àcids de Lewis
Lewis acids
Description
Summary:The alkylation of oxazolones through an SN1 reaction by using stabilized carbocations is reported. The reaction (catalyzed by Brønsted acids, such as TFA or thioureas) affords the final compounds in excellent yields. Reaction with other heterocycles has also been studied, rendering pyrazolone or oxindole derivatives in good yields.

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