Osteoporosis management in patients with chronic kidney disease (ERCOS Study)

Fracture risk assessment in patients with chronic kidney disease (CKD) has been included in the Chronic Kidney Disease-Mineral and Bone Disorders (CKD-MBD) complex in international and national nephrology guidelines, suggesting for the first time the assessment of bone mineral density (BMD) if the r...

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Detalles Bibliográficos
Autores: Bover, Jordi|||0000-0003-3577-2273, Gómez-Alonso, Carlos|||0000-0003-1424-8659, Casado, Enrique|||0000-0001-8839-6430, Rodríguez-García, Minerva, Lloret, Maria Jesus|||0000-0002-1632-7062, Castro-Alonso, Cristina|||0000-0002-8363-1953, Gifre, Laia|||0000-0001-5226-003X, Henríquez-Palop, Fernando|||0000-0002-0231-0745, Prior-Español, Águeda|||0000-0001-5172-9350, López de la Manzanara, Virginia|||0000-0001-6237-3652, Laiz, Ana|||0000-0002-2820-4801, Martínez-Ferrer, Àngels|||0000-0002-5212-2515, Torregrosa, Josep Vicens|||0000-0001-5160-3248, Gigarrán-Guldris, Secundino|||0000-0001-5624-2605, Górriz, José Luis, Montomoli, Marco|||0000-0003-1412-6352, Panizo, Nayara|||0000-0002-1329-2976, Costa, Ester, Martínez-Laguna, Daniel|||0000-0001-5374-8176, Rodríguez, Mariano, Navarro-González, Juan F.|||0000-0002-5015-7474
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:español
OAI Identifier:oai:ddd.uab.cat:304054
Acceso en línea:https://ddd.uab.cat/record/304054
https://dx.doi.org/urn:doi:10.1016/j.nefro.2023.05.002
Access Level:acceso abierto
Palabra clave:BMD
Bone mineral density
Chronic kidney disease
Chronic kidney disease-mineral and bone disorder
CKD-MBD
Densitometry
DXA
Fracture
Osteoporosis
Treatment
Descripción
Sumario:Fracture risk assessment in patients with chronic kidney disease (CKD) has been included in the Chronic Kidney Disease-Mineral and Bone Disorders (CKD-MBD) complex in international and national nephrology guidelines, suggesting for the first time the assessment of bone mineral density (BMD) if the results will impact treatment decisions. However, there is very little information on actual clinical practice in this population. The main objective of the ERC-Osteoporosis (ERCOS) study is to describe the profile of patients with CKD G3-5D with osteoporosis (OP) and/or fragility fractures treated in specialized nephrology, rheumatology and internal medicine clinics in Spain. Fifteen centers participated and 162 patients (mostly women [71.2%] postmenopausal [98.3%]) with a median age of 77 years were included. Mean estimated glomerular filtration rate (eGFR) was 36 ml/min/1.73 m and 38% of the included patients were on dialysis. We highlight the high frequency of prevalent fragility fractures ([37.7%], mainly vertebral [52.5%] and hip [24.6%]), the disproportionate history of patients with glomerular disease compared to purely nephrological series (corticosteroids) and undertreatment for fracture prevention, especially in nephrology consultations. This study is an immediate call to action with the dissemination of the new, more proactive, clinical guidelines, and underlines the need to standardize a coordinated and efficient multidisciplinary care/therapeutic approach to these patients to avoid current discrepancies and therapeutic nihilism.

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