Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains

The Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb.2015.00871

Detalles Bibliográficos
Autores: Fernández, Matilde, Porcel Vílchez, Mario, Torre Zúñiga, Jesús de la, Molina Henares, María Antonia, Daddaoua, Abdelali, Llamas Lorente, María A., Roca, Amalia, Carriel Araya, Victor, Garzón Bello, Ingrid Johanna, Ramos-Martín, Juan Luis, Alaminos Mingorance, Miguel, Duque, Estrella
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/135559
Acceso en línea:http://hdl.handle.net/10261/135559
Access Level:acceso abierto
Palabra clave:Pseudomonas putida
Infecciones hospitalarias
Bacterias patógenas
Virulencia microbiana
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spelling Analysis of the pathogenic potential of nosocomial Pseudomonas putida strainsFernández, MatildePorcel Vílchez, MarioTorre Zúñiga, Jesús de laMolina Henares, María AntoniaDaddaoua, AbdelaliLlamas Lorente, María A.Roca, AmaliaCarriel Araya, VictorGarzón Bello, Ingrid JohannaRamos-Martín, Juan LuisAlaminos Mingorance, MiguelDuque, EstrellaPseudomonas putidaInfecciones hospitalariasBacterias patógenasVirulencia microbianaThe Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb.2015.00871Pseudomonas putida strains are ubiquitous in soil and water but have also been reported as opportunistic human pathogens capable of causing nosocomial infections. In this study we describe the multilocus sequence typing of four P. putida strains (HB13667, HB8234, HB4184, and HB3267) isolated from in-patients at the Besançon Hospital (France). The four isolates (in particular HB3267) were resistant to a number of antibiotics. The pathogenicity and virulence potential of the strains was tested ex vivo and in vivo using different biological models: human tissue culture, mammalian tissues, and insect larvae. Our results showed a significant variability in the ability of the four strains to damage the host; HB13667 did not exhibit any pathogenic traits, HB4184 caused damage only ex vivo in human tissue cultures, and HB8234 had a deleterious effect in tissue culture and in vivo on rat skin, but not in insect larvae. Interestingly, strain HB3267 caused damage in all the model systems studied. The putative evolution of these strains in medical environments is discussed.Work in this study was supported by the ERANET Pathogenomics Program through the ADHERS-Signature Project (reference: BIO2008-04419-E)Peer reviewedFrontiers MediaConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201620162015info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/135559reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglésdoi: 10.3389/fmicb.2015.00871Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1355592026-05-22T06:33:51Z
dc.title.none.fl_str_mv Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
title Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
spellingShingle Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
Fernández, Matilde
Pseudomonas putida
Infecciones hospitalarias
Bacterias patógenas
Virulencia microbiana
title_short Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
title_full Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
title_fullStr Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
title_full_unstemmed Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
title_sort Analysis of the pathogenic potential of nosocomial Pseudomonas putida strains
dc.creator.none.fl_str_mv Fernández, Matilde
Porcel Vílchez, Mario
Torre Zúñiga, Jesús de la
Molina Henares, María Antonia
Daddaoua, Abdelali
Llamas Lorente, María A.
Roca, Amalia
Carriel Araya, Victor
Garzón Bello, Ingrid Johanna
Ramos-Martín, Juan Luis
Alaminos Mingorance, Miguel
Duque, Estrella
author Fernández, Matilde
author_facet Fernández, Matilde
Porcel Vílchez, Mario
Torre Zúñiga, Jesús de la
Molina Henares, María Antonia
Daddaoua, Abdelali
Llamas Lorente, María A.
Roca, Amalia
Carriel Araya, Victor
Garzón Bello, Ingrid Johanna
Ramos-Martín, Juan Luis
Alaminos Mingorance, Miguel
Duque, Estrella
author_role author
author2 Porcel Vílchez, Mario
Torre Zúñiga, Jesús de la
Molina Henares, María Antonia
Daddaoua, Abdelali
Llamas Lorente, María A.
Roca, Amalia
Carriel Araya, Victor
Garzón Bello, Ingrid Johanna
Ramos-Martín, Juan Luis
Alaminos Mingorance, Miguel
Duque, Estrella
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Pseudomonas putida
Infecciones hospitalarias
Bacterias patógenas
Virulencia microbiana
topic Pseudomonas putida
Infecciones hospitalarias
Bacterias patógenas
Virulencia microbiana
description The Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb.2015.00871
publishDate 2015
dc.date.none.fl_str_mv 2015
2016
2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/135559
url http://hdl.handle.net/10261/135559
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv doi: 10.3389/fmicb.2015.00871
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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