Supplementary Information for Broad protection against Invasive fungal disease from a nanobody targeting the active site of fungal β-1,3-glucanosyltransferases [Dataset]

IISA and CSIC adhere to all protocols set by the Committee of Animal Experimentation of the University of Zaragoza, accredited as the Body in Charge of Animal Welfare (OEBA). All experimental procedures comply with FELASA guidelines. In handling animals, we follow the 4Rs rule (Reduction, Refinement...

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Bibliographic Details
Authors: Redrado, Sergio, Macías León, Javier, Castro-López, Jorge, Sanz, Ana Belén, Dolader, Elena, Arias, Maykel, González Ramírez, Andrés Manuel, Sánchez-Navarro, David, Petryk, Yuliya, Farkaš, V., Vincke, Cécile, Muyldermans, Serge, García Barbazán, Irene, Agua, Celia del, Zaragoza, Óscar, Arroyo, Javier, Pardo, Julián, Gálvez Buerba, Eva Mª, Hurtado-Guerrero, R.
Format: conjunto de datos
Publication Date:2024
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/365945
Online Access:http://hdl.handle.net/10261/365945
Access Level:Open access
Keyword:Nanobodies
Fungal cell wall
Aspergillus fumigatus
Cryptococcus
Immunotherapy
Glucanosyltransferases
Transglycosylases
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
Cryptococcus (fungi)
Cryptococcus neoformans
immunotherapy
Description
Summary:IISA and CSIC adhere to all protocols set by the Committee of Animal Experimentation of the University of Zaragoza, accredited as the Body in Charge of Animal Welfare (OEBA). All experimental procedures comply with FELASA guidelines. In handling animals, we follow the 4Rs rule (Reduction, Refinement, Replacement, and Responsibility) as mandated by Royal Decree 53/2013, dated February 1. The degree of animal suffering and/or pain is monitored using the Morton and Griffiths scales, and appropriate measures, such as analgesia or euthanasia, are administered as necessary. Permissions for these procedures were granted under PI33/20 and PI44/20.-- Under a Creative Commons.license BY 4.0.

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