Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients

[Background] Synaptic and extrasynaptic distribution of N-methyl-D-aspartate receptors (NMDARs) has not been addressed in the brain from Alzheimer´s disease (AD) subjects, despite their contribution to neurodegeneration.

Detalles Bibliográficos
Autores: Escamilla, Sergio, Badillos, Raquel, Comella, Joan X., Solé, Montse, Pérez-Otaño, Isabel, Sánchez-Mut, José Vicente, Sáez-Valero, Javier, Cuchillo-Ibáñez, Inmaculada
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/382554
Acceso en línea:http://hdl.handle.net/10261/382554
https://api.elsevier.com/content/abstract/scopus_id/85205221309
Access Level:acceso abierto
Palabra clave:Alzheimer´s disease
GluN1
GluN2A
GluN2B
GluN3A
NMDA
Tyr1336
Tyr1472
Extrasynaptic
Human
Descripción
Sumario:[Background] Synaptic and extrasynaptic distribution of N-methyl-D-aspartate receptors (NMDARs) has not been addressed in the brain from Alzheimer´s disease (AD) subjects, despite their contribution to neurodegeneration.