Design and construction of a photoacoustic imaging setup

Photoacoustic Microscopy (PAM) is a novel imaging technique that is commonly used with samples composed by soft tissue and that can provide penetration beyond the optical diffusion limit while maintaining high resolution. By using a short-pulsed laser to irradiate the tissue, part of the light energ...

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Bibliographic Details
Author: Rodrigo Arcay, Noel|||0000-0003-0701-3640
Format: master thesis
Publication Date:2016
Country:España
Institution:Universitat Politècnica de Catalunya (UPC)
Repository:UPCommons. Portal del coneixement obert de la UPC
Language:English
OAI Identifier:oai:upcommons.upc.edu:2117/90729
Online Access:https://hdl.handle.net/2117/90729
Access Level:Open access
Keyword:Imaging systems in medicine
photoacoustic microscopy
ultrasound
acoustics
imaging
instrumentation
Imatges mèdiques -- Tractament
Àrees temàtiques de la UPC::Enginyeria de la telecomunicació::Processament del senyal::Processament de la imatge i del senyal vídeo
Description
Summary:Photoacoustic Microscopy (PAM) is a novel imaging technique that is commonly used with samples composed by soft tissue and that can provide penetration beyond the optical diffusion limit while maintaining high resolution. By using a short-pulsed laser to irradiate the tissue, part of the light energy is converted into heat, which induces the formation of acoustic waves that propagate inside the tissue and can be detected through ultrasound transducers. In this way, the absorption coefficient can be used as a contrast property of the matter, allowing the mapping of biological and chemical information. The essence of this master thesis is the design and start up of a PAM setup. This report contains the explanation of the different steps performed before reaching this goal, together with a justification of the different decisions that were taken along its construction. Finally, the resulting device and its main features are shown and discussed.