Occurrence of extended-spectrum beta-lactamase producing Salmonella enterica in North Spain with evidence of CTX-M-9 clonal spread among animals and humans

Among the 1233 Salmonella enterica isolates obtained in two Spanish hospitals, five isolates (0.4%) (serovars: Virchow, four; Livingstone, one) had the phenotype of an extended-spectrum β-lactamase (ESBL) producer. The genetic characterization of the ESBL of S. enterica Livingstone revealed a bla SH...

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Detalles Bibliográficos
Autores: Riaño, I. [0000-0001-8410-2706], García-Campello, M., Sáenz, Y. [0000-0002-2457-4258], Álvarez, P., Vinué, L. [0000-0001-7459-0814], Lantero, M., Moreno, M.Á. [0000-0002-5357-3684], Zarazaga, M. [0000-0002-8703-5489], Torres, C. [0000-0003-3709-1690]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:España
Institución:Universidad de La Rioja (UR)
Repositorio:RIUR. Repositorio Institucional de la Universidad de La Rioja
OAI Identifier:oai:portal.dialnet.es:doc/5bbc6994b750603269e81dd7
Acceso en línea:https://investigacion.unirioja.es/documentos/5bbc6994b750603269e81dd7
Access Level:acceso abierto
Palabra clave:CTX-M-10
CTX-M-9
Salmonella enterica
SHV-2
Descripción
Sumario:Among the 1233 Salmonella enterica isolates obtained in two Spanish hospitals, five isolates (0.4%) (serovars: Virchow, four; Livingstone, one) had the phenotype of an extended-spectrum β-lactamase (ESBL) producer. The genetic characterization of the ESBL of S. enterica Livingstone revealed a bla SHV-2 gene. The bla CTX-M-10 gene in a phage-related genetic environment was found in one S. enterica Virchow isolate, and the bla CTX-M-9 gene within the In60 integron was found in the three remaining Virchow isolates. These three isolates presented indistinguishable or closely related pulsed-field gel electrophoresis patterns among themselves and also as compared with the two other bla CTX-M-9-containing isolates previously obtained from animals. ESBL production is an emerging mechanism of resistance in S. enterica in the two studied hospitals. © 2009 The Authors Journal compilation © 2009 European Society of Clinical Microbiology and Infectious Diseases.